There are varieties of traditional medicinal plants widely used for boosting memory. These include Bacopa monnieri, Rhodiola rosea, Ginkgo biloba, Withania somnifera, etc. Memory effect such is solely attributed to their active phytoconstituents. constituents also referred as smart drugs. capable crossing blood brain barriers. They enhance the cognitive performance in by acting on memory make i...

OBJECTIVE The objective of this paper is to review the literature regarding Withania somnifera (ashwagandha, WS) a commonly used herb in Ayurvedic medicine. Specifically, the literature was reviewed for articles pertaining to chemical properties, therapeutic benefits, and toxicity. DESIGN This review is in a narrative format and consists of all publications relevant to ashwagandha that were i...

The herbicidal activity of Withania somnifera (L.) Dunal against the noxious weed parthenium (Parthenium hysterophorus L.) was evaluated. In a laboratory bioassay, the effect of aqueous, methanol and n-hexane shoot and root extracts of 5%, 10%, 15% and 20% w/v concentrations (on a fresh weight basis) of W. somnifera were tested against the germination and seedling growth of parthenium. In gener...

BACKGROUND Sterol glycosyltrnasferases (SGT) are enzymes that glycosylate sterols which play important role in plant adaptation to stress and are medicinally important in plants like Withania somnifera. The present study aims to find the role of WsSGTL1 which is a sterol glycosyltransferase from W. somnifera, in plant's adaptation to abiotic stress. METHODOLOGY The WsSGTL1 gene was transforme...

Withania somnifera is one of the most valuable medicinal plants used in Ayurvedic and other indigenous medicine systems due to bioactive molecules known as withanolides. As genomic information regarding this plant is very limited, little information is available about biosynthesis of withanolides. To facilitate the basic understanding about the withanolide biosynthesis pathways, we performed tr...

The present experiment was aimed to assess imidacloprid induced alterations in oestrous cycle and ameliorative effects of Withania somnifera rats. 48 female albino Wistar rats were divided into four groups 12 animals each. Group 1 is control, group 2 (30 mg/kg body weight/d), 3 (1 g/kg feed) 4 imidacloprid+Withania weight/ d+1 feed). test chemical administered daily by oral gavage for 30 d. Sev...

Withania somnifera (ashwagandha) is a widely used herb in the Ayurvedic system of medicine. The objective of the present study was to elucidate the effect of W. somnifera root extract (Ws) alone or in combination with exogenous gamma-amino butyric acid (GABA), a GABA receptor agonist or with diazepam, a GABA receptor modulator against pentylenetetrazol (PTZ, iv) seizure threshold in mice. Minim...

Introduction and Aim: Withania somnifera, called as Indian Ginseng is a very important plant in traditional medicinal practices. The possesses wide range of activity has been used to treat multiple diseases. anti-inflammatory, neuroprotective, hypoglycemic, antiarthritic, hepatoprotective, antioxidant, anti-stress, immunostimulatory anti-cancer therapeutic activities. Cancer health burden preva...