Abstract Funding Acknowledgements Type of funding sources: Foundation. Main source(s): This study was mainly supported from the British Heart Foundation (BHF) supporting Prof. Manuel Mayr as a Chair Holder (CH/16/3/32406) with BHF programme grant support (RG/16/14/32397) and Dr. Theofilatos programm (G/20/10387). Background Using proteomics, we strove to reveal novel molecular subtypes human at...

As silicon is known to have a positive role in enhancing the resistance of rice plants insects, an investigation on one aspect biochemical and molecular basis plant defences mediated by amendments against brown hopper Nilaparvata lugens (Stål), comprising field, pot culture laboratory experiments was undertaken OUAT. Two organic products; Diatomaceous Earth (DAE) at 0.15, 0.30 0.45 t/ha, Rice H...

background enterococcus faecium is an important nosocomial pathogen and has developed resistance to multiple antibiotics, such as vancomycin. nitrofurantoin is active against e. faecium and e. faecalis, including vana- and vanb-positive isolates. objectives to investigate the role of rpob mutation in e. faecium. methods the growth rate and reactive oxygen species (ros) levels were determined. t...

pathological changes within an organ can be reflected as proteomic patterns in biological fluids such as plasma, serum, and urine. the surface-enhanced laser desorption and ionization time-of-flight mass spectrometry (seldi-tof ms) has been used to generate proteomic profiles from biological fluids. mass spectrometry yields redundant noisy data that the most data points are irrelevant features ...

Progresses in screening, early diagnosis, prediction of aggressiveness and of therapeutic response or toxicity, and identification of new targets for therapeutic will improve survival of breast cancer. These progresses will likely be accelerated by the new proteomic techniques. In this review, we describe the different techniques currently applied to clinical samples of breast cancer and the mo...

Progresses in screening, early diagnosis, prediction of aggressiveness and of therapeutic response or toxicity, and identification of new targets for therapeutic will improve survival of breast cancer. These progresses will likely be accelerated by the new proteomic techniques. In this review, we describe the different techniques currently applied to clinical samples of breast cancer and the mo...

A comparison of extracellular proteins of virulent and avirulent Edwardsiella tarda strains revealed several major, virulent-strain-specific proteins. Proteomic analysis identified two of the proteins in the virulent strain PPD130/91 as flagellin and SseB, which are virulence factors in bacterial pathogens. PCR amplification and DNA sequencing confirmed the presence of the genes that encode the...

Citation: Papadopoulou ES, Perruchon C, Vasileiadis S, Rousidou C, Tanou G, Samiotaki M, Molassiotis A and Karpouzas DG (2018) Metabolic and Evolutionary Insights in the Transformation of Diphenylamine by a Pseudomonas putida Strain Unravelled by Genomic, Proteomic, and Transcription Analysis. Front. Microbiol. 9:676. doi: 10.3389/fmicb.2018.00676 Metabolic and Evolutionary Insights in the Tran...

Milk fat globules memebrane (MFGM)-enriched proteomes from Holstein, Jersey, yak, buffalo, goat, camel, horse, and human were extracted and identified by an iTRAQ quantification proteomic approach. Proteomes data were analyzed by bioinformatic and multivariate statistical analysis and used to present the characteristic traits of the MFGM proteins among the studied mammals. The data of this stud...

Proteomic profiling of mitochondria has the potential to provide insights into mitochondrial functions associated with aging, various metabolic states, and diseases such as cancer, diabetes, and cardiovascular disease [1]. Rapid and reproducible isolation of intact mitochondria is crucial for efficient enrichment and subsequent proteomic analysis of low-abundance mitochondrial proteins [2]. Her...