نتایج جستجو برای: proteomics techniques
تعداد نتایج: 656517 فیلتر نتایج به سال:
Proteomics belongs to the group of so called “ omics ” technologies that are preferentially exploited for the global analysis of temporal or conditional alterations in gene expression, on either the gene or protein level. Proteomics is focused on proteins and provides information about their abundances, post translational modifi cations, localization and mutual interactions. Current proteomic p...
information avalanche (overload or expansion) in various scientific fields is a novel issue turned out by a number of factors considered necessary to facilitate their record and registration. though, the biological science and its diverse fields like proteomics are not immune of this event and even may be as the event’s herald. on the other hand, time as the most valued anxiety of human has enc...
Cancer is the second leading cause of death worldwide; it can be successfully treated in early stages. Screening for cancer should performed safe, accurate, cost-effective, and non-invasive techniques therefore achieved patient convenience. The salivary diagnosis could a promising era oncological fields, which have some correlations with serum biomarkers certain cancers. In this paper, we revie...
Infectious diseases are still a major health risk, and thus a better understanding of the interaction between human host cells and pathogenic microbes is urgently required. Since the interplay between both partners is highly complex, genome-wide analysis by OMICs approaches will likely make a major contribution to the elucidation of the pathophysiology of infection processes. In the concert of ...
High-throughput techniques for genomics and proteomics differ greatly from traditional bio-molecular research techniques in the amount of data that can be obtained from a given experiment. However, many of these novel techniques rely heavily on the traditional concepts of molecular immobilization followed by hybridization, binding or analysis. These concepts, which predate even traditional blot...
different treatment strategies of alzheimer's disease (ad) are being studied for treating or slowing the progression of ad. many pharmaceutically important regulation systems operate through proteins as drug targets. here, we investigate the drug target proteins in beta-amyloid (aβ) injected rat hippocampus treated with lavandula angustifolia (la) by proteomics techniques. the reported stu...
Background: Proteomics is rapidly evolving into a high-throughput technology, in which substantial and systematic studies are conducted on samples from a wide range of physiological, developmental, or pathological conditions. Reference maps from 2D gels are widely circulated. However, there is, as yet, no formally accepted standard representation to support the sharing of proteomics data, and l...
Despite many recent advances in instrumentation, the sheer complexity of biological samples remains a major challenge in large-scale proteomics experiments, reflecting both the large number of protein isoforms and the wide dynamic range of their expression levels. However, while the dynamic range of expression levels for different components of the proteome is estimated to be ∼107-8, the equiva...
Increased efforts have been made during the last few decades to develop new technologies capable of identifying and quantifying the expression proteome in different cellular systems in physiological and physiopathological conditions for determining illness biomarkers, pharmaceutical targets and/or posttranslational modifications (PTM) by means of proteomic techniques. 2D gel electrophoresis, wi...
With the advancement in proteomics separation techniques and improvements in mass analyzers, the data generated in a mass-spectrometry based proteomics experiment is rising exponentially. Such voluminous datasets necessitate automated computational tools for high-throughput data analysis and appropriate statistical control. The data is searched using one or more of the several popular database ...
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