Platelet-rich plasma (PRP) is defined as a portion of the plasma fraction of autologous blood having platelet concentrations above baseline. When activated the platelets release growth factors that play an essential role in bone healing such as Platelet-derived Growth Factor, Transforming Growth Factor-β, Vascular Endothelial Growth Factor and others.Multiple basic science and in vivo animal st...

conclusions our study demonstrates positive results (preservation or regeneration of bone) using prp in treatment of bronj. although prp may enhance osseous regeneration, long-term follow-ups are required to confirm its benefits. background bisphosphonate-related osteonecrosis of the jaws (bronj) is a well-known challenging entity warranting management. platelet-rich plasma (prp) plays an impor...

Background: Corrosive esophageal burns have high morbidity and mortality. The effective treatment is controversial. In our study, we aimed to examine the effects of resveratrol (RSV) platelet rich plasma (PRP) on healing in corrosive esophagitis model rats. 
 Material methods: A total 24 rats were randomly divided into 4 groups each as esophagitis, control, PRP RSV groups. No was administe...

Myocardial infarction is the leading cause of death in world’s population. The sudden and progressive loss cardiomyocyte contractile cells due to disproportionate number new formation. This pathological condition will ultimately reduce function heart muscles. Platelet-rich plasma (PRP) last decade has been attracting attention regarding its role cell regeneration. content cytokines growth facto...

BACKGROUND Concentrated leukocytes in leukocyte- and platelet-rich plasma (L-PRP) may deliver increased levels of pro-inflammatory cytokines to activate the NF-κB signaling pathway, to counter the beneficial effects of growth factors on osteoarthritic cartilage. However, to date no relevant studies have substantiated that in vivo. MATERIAL AND METHODS Autologous L-PRP and pure platelet-rich pla...

Objective: The objective of this study was to assess average improvement in maximal mouth opening, pain at rest, and active opening after platelet-rich plasma (PRP) injections using ultrasonography (USG)-guided platelets rich injection the management internal derangement joint. Materials Methods: Ten patients with temporomandibular joint (TMJ) underwent PRP guided by ultrasonography. extent pai...

  Background: Osteoarthritis is a disabling musculoskeletal disease with no definite treatment. This study compared the effect of Platelet-rich plasma (PRP) and Transcutaneous Electrical Nerve Stimulation (TENS) plus exercise in the treatment of patients with knee joint osteoarthritis.   Methods : 54 eligible patients with knee osteoarthritis were randomly allocated into two groups. (IRCT201211...