Background: Pruritic skin disorders are one of the most common disorders in elderly. Objective: To find out the prevalence of pruritic skin disorders in the elderly residing in Kahrizak Institute in Tehran. Patients and Methods: In this descriptive, cross sectional survey, all the elderly over 60 years of age without dementia residing in Kahrizak Institute in Tehran in the first 6 months ...

Sirolimus is an immunosuppressant drug used to prevent organ rejection in transplant patients. We describe a man with sirolimus-associated pruritus and review the features of this adverse event in other individuals receiving this drug. The patient was a 67-year-old heart transplant recipient receiving sirolimus as part of his immunosuppressive regimen. He developed severe pruritus over the dist...

Twenty-seven pruritic dogs were used in this study. When a hypoallergenic diet was fed to these 27 dogs for six weeks, none of the dogs showed improvement of the pruritus. These dogs had a history and clinical signs of atopic dermatitis (AD) as defined by Prelaud's diagnostic criteria. Subsequently, the 27 dogs were isolated for observation for two weeks in the hospital. In the isolation room i...

BACKGROUND Hydrolysed protein diets are used to diagnose and treat dogs with cutaneous adverse food reactions (CAFR). Little is known about what proportion of dogs hypersensitive to the native protein would react to its hydrolysed form. OBJECTIVES To determine the clinical allergenicity of hydrolysed poultry feather (RCU) and chicken liver diets (HZD) in dogs with chicken induced CAFR. METH...

Pruritus is a major symptom of several dermatological diseases but has limited therapeutic options available. Animal models replicating the pathophysiology of pruritus are needed to support the development of new drugs. Induction of pruritus by chloroquine (CQ) in mice is widely used, although, as with similar models, it has low throughput and does not distinguish between antipruritic effects a...

BACKGROUND The cause of brachioradial pruritus (a localized itching on the arms or shoulders) is controversial. A hereditary form of this condition has not been reported. OBJECTIVES To describe the occurrence of brachioradial pruritus in several members of one family. PATIENTS AND METHODS The pedigree of the three generations and the history of brachioradial pruritus was outlined. Four sist...

1. Kittisupamongkol W. Not all that itches is uraemic pruritus. Nephrol Dial Transplant 2009; doi: 10.1093/ndt/gfp239 2. Pauli-Magnus C, Mikus G, Alscher DM et al. Naltrexone does not relieve uremic pruritus: results of a randomized, double-blind, placebocontrolled crossover study. J Am Soc Nephrol 2000; 11: 514–519 3. Neilly J, Martin A, Simpson N et al. Pruritus in diabetes mellitus: investig...

INTRODUCTION Atopic dermatitis (AD) and psoriasis are chronic inflammatory skin diseases frequently accompanied by itching. The exact pathogenesis of dermatological pruritus remains unknown, but it is believed that altered skin innervation may play a role. AIM The assessment of the sensory threshold in AD and psoriasis in relation to pruritus experienced by patients. MATERIAL AND METHODS A ...

BACKGROUND Dry skin is frequently observed in uraemic patients and a link with the common complaint of pruritus has been suggested. Objective data on skin dryness in haemodialysed patients is sparse and equivocal. No such information exists for the many patients now receiving peritoneal dialysis. We assessed the prevalence and severity of both pruritus and skin dryness in a uraemic population r...