نتایج جستجو برای: psa density
تعداد نتایج: 421710 فیلتر نتایج به سال:
Objective To investigate potential associations of preoperative total testosterone (TT) with tumor volume (TV) and grade of prostate cancer (PCa). Methods Patients who were under medications impacting on the hypothalamic-pituitary-adrenal-testis-prostate axis were excluded. TT was measured preoperatively at least 1 month after biopsies and TV was calculated on the removed prostate specimen. O...
زمینه و هدف: آستانه خاص آنتیژن اختصاصی پروستات (prostate specific antigen-psa) برای مشخص نمودن بیماران در معرض بالاترین خطر ابتلا به سرطان پروستات همیشه بحث برانگیز بوده است. این مطالعه با هدف بررسی میزان مقادیر psa بر اساس سن و بررسی رابطه psa و نمایه توده بدن (body mass index-bmi) و در افراد بدون علامت انجام شده است. روش کار: در این مطالعه توصیفی از اطلاعات دموگرافیک و مقادیر psa در 180 نف...
OBJECTIVE To explore effects on serum lipids, pituitary-gonadal axis, prostate and bone turnover of the administration of the mixed oestrogen agonist/antagonist raloxifene in healthy elderly men. PARTICIPANTS Thirty healthy men aged 60-70 years randomly received raloxifene 120 mg/day (n=15) or placebo (n=15) for 3 months. MEASUREMENTS In this double-blind, placebo-controlled study, serum go...
زمینه و هدف: آنتی ژن اختصاصی پروستات (psa)، بهترین مارکر برای تشخیص زودهنگام سرطان پروستات می باشد. از آنجایی که سن و نژاد از جمله عوامل تأثیرگذار بر سطح psa می باشند، تعیین محدوده مرجع وابسته به سن psa در هر جامعه، برای افزایش میزان کارایی آزمون psa ضروری می باشد. هدف از این مطالعه بررسی توزیع نرمال tpsa (total psa) و fpsa (free psa) و تعیین محدوده مرجع مختص سن psa در مردان ایرانی بوده است. رو...
INTRODUCTION Diverse bone pathologies are observed in patients with psoriatic arthritis (PsA). Uncoupling of bone remodeling with disordered osteoclastogenesis has been implicated in the pathogenesis of PsA. The aim of this study was to examine the role of soluble mediators of bone remodeling within the circulation of patients with PsA. METHODS Patients with PsA (n = 38), with psoriasis (n = ...
BACKGROUND Measurement of prostate-specific antigen (PSA) in prostate cancer patients following radical prostatectomy (RP) has been hindered by the limit of quantification of available assays. Because radical prostatectomy removes the tissue responsible for PSA production, postsurgical PSA is typically undetectable with current assay methods. Evidence suggests, however, that more sensitive dete...
Circulating levels of prostate-specific antigen (PSA) and testosterone are widely used for the detection of prostate cancer prior to prostate biopsy; however, both remain controversial. Effective screening strategies based on quantitative factors could help avoid unnecessary biopsies. Here, we sought to clarify the predictive value of free testosterone (FT) vs total testosterone (TT) in identif...
Prostate cancer is the most commonly diagnosed malignancy and second leading cause of cancer-related death for men in the United States. The introduction and routine use of serum prostate-specific antigen (PSA) testing in men at risk for the disease has led to significant changes in prostate cancer incidence, presentation and treatment. It is believed that these changes will eventually translat...
Objective To configure and validate a novel prostate disease nomogram providing prostate biopsy outcome probabilities from a prospective study correlating clinical indicators and diagnostic parameters among Filipino adult male with elevated serum total prostate specific antigen (PSA) level. Methods All men with an elevated serum total PSA underwent initial prostate biopsy at our institution f...
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