نتایج جستجو برای: psa kinetics
تعداد نتایج: 108543 فیلتر نتایج به سال:
conclusions psa, psa density, and gleason score should be considered together in order to more accurately predict the adverse pathologic features of prostate cancer. methods we conducted a cross-sectional study of 105 patients with localized prostate cancer who underwent radical prostatectomy between 2006 and 2013. we recorded gleason scores and psa levels, in addition to the results of patholo...
background: prostate specific antigen (psa) is an important laboratory marker for diagnosis of prostatic cancer. thus, development of diagnostic tools specific for psa plays an important role in screening, monitoring and early diagnosis of prostate cancer. in this paper, the production and characterization of a panel of murine monoclonal antibodies (mabs) against psa have been presented. metho...
123 Background: Restaging with PET-CT in biochemical recurrent prostate cancer after prostatectomy shows a higher frequency of (false) negative cases compared to restaging after EBRT. It is uncertain if this reflects low volume of disease and/or low grade as biopsies fail to prove recurrent cancer in 50% of cases. We followed the clinical course of men with recurrent prostate cancer (PCa) after...
BACKGROUND Immunoassays to measure prostate-specific antigen (PSA) often give different values for the same patient samples, and the calibrators among commercial immunoassays are not interchangeable. We developed three novel assays to quantify the free and complexed forms of PSA in serum. METHODS We synthesized 46 peptides, which encompassed the entire PSA molecule, and determined the interac...
We report our experience with 124 patients were referred 70 our urology clinic in Sina hospital for urinary retention. Serum PSA analyzed by using a monoclonal assay. All patients underwent digital rectal examination. The patients devided in 3 groups: Group 1 (87 men) with a serum PSA level less than 4 ng/ml, group 2 (26 men) with a serum PSA level 4-10 ng/ml and group 3 (11 men) with a serum P...
Background & Aims: The use of TURP in detecting prostate cancer in patients with elevated PSA levels and positive lower urinary tract symptoms (LUTS) is controversial. In the present study we evaluated the role of TURP in detecting prostate cancer in these patients. Materials & Methods: In this cross-sectional study a total of 40 patients with elevated PSA levels, positive LUTS and negative 10-...
عقیده بر این است که فاکتور رشد شبه انسولینی نوع i (igf-i)، که غلظت آن به طور عمده توسط هورمون رشد کنترل می شود، تکثیرو تمایز سلول های زایا را تحت تاثیر قرارمی دهد. عملکرد این فاکتور متأثر از پروتئین های متصل شونده به آن (igfbps) و آنتی ژن اختصاصی پروستات (psa) است. هدف از این مطالعه بررسی میزان سطح سرمی و پلاسمای سمینال igf-i و psa در مردان مبتلا به ناباروری ایدیوپاتیک بود. به همین منظور مطالعه...
INTRODUCTION Although prostate cancer (PCa) incidence is lower in HIV+ men than in HIV- men, the usefulness of prostate-specific antigen (PSA) screening in this population is not well defined and may have higher false negative rates than in HIV- men. We aimed to describe the kinetics and predictive value of PSA in HIV+ men. METHODS Men with PCa (n=21) and up to two matched controls (n=40) wit...
To study immunorecognition of free type and complex type prostate-specific antigen (PSA) by current commercial PSA assays, sera from 3 patients with stage D2 prostate cancer were separated by Sephacryl S-200 chromatography and determined by Delfia PSA, ACS-PSA and Eiken PA kits. Two antibodies used in the 3 kits are 2 monoclonal, 1 monoclonal and 1 polyclonal and 2 polyclonal antibodies, respec...
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