Centrosome duplication is indispensable for the formation of the bipolar mitotic spindle. Surprisingly, even if DNA replication or mitosis is inhibited, centrosome duplication can still occur [1] [2] [3] [4] [5]. Thus, it remains unknown how centrosome duplication is coordinated with the cell cycle. Here, we show that centrosome duplication requires cyclin-dependent kinase 2 (Cdk2) in mammalian...

We report here a very rare case of de novo inversion-duplication chromosomal abnormality with a pure 3qter duplication syndrome. Interestingly, the 3q duplication includes an overlap of the syndromes critical region. Although there have only been 9 cases of this syndrome reported in the past, our patient had more severe neurological abnormalities than anticipated. In this regard, we have gather...

In this paper, we propose a task duplication based scheduling algorithm for avoiding useless duplication. In our algorithm, task duplication is divided into two phases: a task fill phase and a task duplication phase. In the task fill phase, tasks are duplicated and allocated to idle time slots in used processors. Namely, the task fill phase does not require additional idle processors. The task ...

We present here the first prenatal diagnosis of 17p13.1p13.3 duplication. 17p13.3 duplication has recently been defined as a new distinctive syndrome with several diagnosed patients. In the current case prenatal chromosome analysis (G-banding) performed on cultured amniocytes revealed additional material in chromosome 19p. This was further defined as a chromosome 17p13.1p13.3 duplication by FIS...

Bladder duplication is a rare congenital anomaly which occurs in the sagittal or coronal plane and it can be associated with other anomalies. It has been previously classified as complete duplication of the bladder and urethra or incomplete duplication with two bladders and common urethra. However, complete duplication of bladder with a single urethra has been rarely reported. Herein, we presen...

In animal cells, duplication of centrosomes and DNA is coordinated. Since CDK2/cyclin E triggers initiation of both events, activation of CDK2/cyclin E is thought to link these two events. We identified nucleophosmin (NPM/B23) as a substrate of CDK2/cyclin E in centrosome duplication. NPM/B23 associates specifically with unduplicated centrosomes, and NPM/B23 dissociates from centrosomes by CDK2...

Duplication is the simplest fault-detection technique. Here, two identical copies are used and when a failure occurs, the two copies are no longer identical. A simple comparison detects the fault. Duplication detects all single faults except for that of the comparator. Duplication is applicable to all areas and levels of computer design, and thus is widely used. Let us now look at examples of c...

We introduce a new triangle transformation, the shortest-edge (SE) duplication, as natural way of mesh derefinement suitable to those meshes obtained by iterative application longest-edge bisection refinement. Metric properties SE duplication in region normalised triangles endowed with Poincare hyperbolic metric are studied. The self-improvement this transformation is easily proven, well minimu...