نتایج جستجو برای: psoriasis
تعداد نتایج: 17624 فیلتر نتایج به سال:
BACKGROUND A 6-year-old girl with a symmetric linear eruption on both of her legs, clinically and histologically resembling inflammatory linear verrucous epidermal nevus (ILVEN) or linear psoriasis (LP), with concomitant psoriasis of the guttata type and a positive family history of psoriasis is presented. The questions as to whether LP actually exists and ILVEN represents a distinct entity are...
BACKGROUND Estimates of psoriatic arthritis (PsA) prevalence among psoriasis patients vary widely (5-40%). The time to development of PsA in patients with plaque psoriasis also remains unclear. OBJECTIVES To examine whether length of time since diagnosis of psoriasis affects risk of developing PsA, and to assess differences in quality of life (QoL), work-related issues, comorbidities and heal...
Psoriasis is characterized by an apoptosis-resistant and metabolic active epidermis, while a hallmark for allergic contact dermatitis (ACD) is T cell-induced keratinocyte apoptosis. Here, we induced ACD reactions in psoriasis patients sensitized to nickel (n = 14) to investigate underlying mechanisms of psoriasis and ACD simultaneously. All patients developed a clinically and histologically typ...
conclusions patients’ experiences of stigma and rejection phenomena indicated that all aspects of their lives are affected. moreover, these findings highlight the significance of stigma and rejection concepts in providing better care to these patients. results after analysis of interviews, four themes were extracted: lack of social support, unrealistic and inappropriate labeling, rejection and ...
BACKGROUND To date, there is no global consensus on the definition of the severity of psoriasis. The REFlective evaLuation of psoriasis Efficacy of Treatment and Severity (REFLETS) questionnaire has recently been developed to provide a better understanding of plaque-type psoriasis severity and treatment efficacy from both patient and clinician perspectives. OBJECTIVE This study aimed to devel...
OBJECTIVE To examine the association between total physical activity, walking, and vigorous exercise and the incidence of psoriasis in women. DESIGN Cohort study. SETTING The Nurses' Health Study II, a cohort of 116,430 women aged 27 to 44 years in 1991. PARTICIPANTS The study population included 86,655 US female nurses who reported whether they had ever been diagnosed as having psoriasis...
UNLABELLED Psoriasis is a chronic inflammatory disease of the skin which affects 1-3% of the population. A higher association of metabolic syndrome (MS) has been described amongst sufferers. The objective of this study was to assess the association of MS and its components amongst subjects suffering psoriasis and compare it with that found for the control group. The secondary objective was to s...
Psoriasis is a chronic, immune-mediated skin disease affecting approximately 1% to 3% of the human immunodeficiency virus (HIV)-infected population. The presentation of psoriasis in patients with HIV varies. It either presents as the first clinical manifestation of HIV or, less commonly, appears in the advanced stages of HIV when it has progressed to AIDS. This 2-part series reviews the pathoge...
Dresden (29. März 2011) – Neben der Psoriasis vom Plaque-Typ sind in den letzten Jahren auch andere Manifestationen dieser häufigen Hauterkrankung zunehmend in den Blickpunkt des Interesses gerückt, darunter Plaque-Psoriasis mit Nagelbeteiligung und Psoriasis-Arthritis (PsA) sowie eine Vielzahl weiterer bedeutsamer Komorbiditäten. Dies hat unter anderem zur Implementierung von Therapieund Ver...
BACKGROUND Psoriasis is the disease of abnormal keratinocyte differentiation and apoptosis. Alterations in DNA methylation leading to keratinocyte hyperproliferation is one of the proposed pathogenic mechanisms of psoriasis. B-cell receptor associated protein (BCAP31) has been reported to be involved in the proliferation and apoptosis of keratinocytes. Up-regulation and changing in BCAP31 promo...
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