نتایج جستجو برای: pulmonary tb
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Background and Aim: Despite the implementation of effective preventive and therapeutic programs, no significant success has been achieved in the reduction of tuberculosis. One of the reasons is the delay in diagnosis. Therefore, the creation of a diagnostic aid system can help to diagnose early Tuberculosis. The purpose of this research was to evaluate the role of the Naive Bayes algorithm as a...
Background and Objectives: One of the applications of population attributable risk percent (PAR%) is to estimate the disease burden in a population exposed to several risk factors. Therefore, this study was conducted to estimates the PAR% of the space-time clusters of pulmonary tuberculosis. Methods: In this study, the data of pulmonary TB cases were obtained from the health department of Ha...
Purpose] Mycobacterium tuberculosis (MTB) infection should be detected in all patients before progressing to active tuberculosis (TB) ; however, interferon-γ release assays (IGRAs) and serological assays cannot accurately detect TB infection in all patients. Therefore, we conducted a prospective study to determine whether TB infections in patients with active pulmonary TB could be reliably dete...
Background and objective There are no recent data on the prevalence of drug-resistant tuberculosis (DR TB) in Cambodia. We aim to describe TB drug resistance amongst adults with pulmonary and extra-pulmonary TB and human immunodeficiency virus (HIV) co-infection in a national referral hospital in Phnom Penh, Cambodia. Design Between 22 November 2007 and 30 November 2009, clinical specimens from...
Background: On tuberculosis control standpoint, the treatment of children with TB is not considered a priority as they rarely transmit the disease and contribute little to the maintenance of the tuberculosis epidemic. Therefor this study conducted to describe pediatric TB cases, and to identify pattern of risk factors in non-endemic communities Materials and Methods: The present cross- sectiona...
Background: Tuberculosis (TB) is a major global cause of mortality and morbidity, and host genetic factors influence disease susceptibility. Interferon-c mediates immunity to mycobacteria and rare mutations in the interferon-c receptor-1 gene (IFNGR1) result in increased susceptibility to mycobacterial infection, including TB, in affected families. The role of genetic variation in IFNGR1 in sus...
BACKGROUND Diseases caused by Mycobacterium tuberculosis (TB) among adult patients with hematological malignancies have rarely been investigated. METHODS Adult patients with hematological malignancies at National Taiwan University Hospital between 1996 and 2009 were retrospectively reviewed. Patients with positive serology for HIV were excluded. TB disease is diagnosed by positive culture(s) ...
BACKGROUND Single nucleotide polymorphisms (SNPs) within precursor microRNAs (miRNAs) can affect miRNAs expression, and may be involved in the pathogenesis of pulmonary tuberculosis (TB). This study aimed to investigate potential associations between the four precursor miRNA SNPs (miR-146a C > G, miR-149 T > C, miR-196a2 T > C, and miR-499 T > C) and susceptibility to pulmonary TB in the Chines...
Tuberculosis (TB) is decreasing in the European Union/ European Economic Area (EU/EEA), but remains a significant public health problem. Although pulmonary TB accounts for the majority of the cases and is the main transmissible form of the disease, extrapulmonary TB also contributes to the burden of disease and does not receive specific attention in international control strategies. We performe...
Objective: To determine the diagnostic sensitivity of bacteriological analyses in induced sputum (IS) for the diagnosis of pulmonary tuberculosis (TB) and to identify the clinical characteristics associated with the confirmed diagnosis, as well as to determine the diagnostic yield of bronchoscopy carried out when IS tests negative for AFB in smear microscopy. Methods: A retrospective, cross-sec...
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