نتایج جستجو برای: pyrazole derivative

تعداد نتایج: 66771  

2011
Artur Korzański Pawel Wagner Maciej Kubicki

In the crystal structure of the title compound, C(9)H(8)ClN(3), amino-pyrazole N-H⋯N hydrogen bonds connect the mol-ecules along the [010] direction; the chains interact with each other only by van der Waals-type inter-actions. The pyrazole and phenyl rings are inclined at a dihedral angle of 45.65 (6)°

2010
M. Kannan Kandhasamy Kumaravel Gnanasambandam Vasuki R. Krishna

In he title compound, C(13)H(16)N(4)O(3), the pyrazole ring is planar (r.m.s. deviation = 0.054 Å). The pyran ring is not planar; the mean plane makes a dihedral angle of 1.9 (1)° with the pyrazole ring. In the crystal structure, inter-molecular N-H⋯N and N-H⋯O inter-actions lead to a linear chain motif.

Journal: :Molecules 2014
Khaled R A Abdellatif Eman K A Abdelall Mohamed A Abdelgawad Rasha R Ahmed Rania B Bakr

3,6-Dimethyl-1-phenyl-1H-pyrazolo[3,4-d][1,3]oxazin-4-one (3) was prepared by hydrolysis of ethyl 5-amino-3-methyl-1-phenyl-1H-pyrazole-4-carboxylate (1) to afford the corresponding carboxylic acid 2, which was reacted with acetic anhydride to give 3. The pyrazolo[3,4-d][1,3]oxazin-4-one 3 was reacted with hydroxylamine hydrochloride, urea, thiourea, thiosemicarbazide, phenylhydrazine and aroma...

Journal: :New Journal of Chemistry 2023

Synthesis and molecular docking of pyrazole derivatives using the heterogeneous basic, CS-DAA/MgO nanocomposite.

Journal: :Chemistry 2023

Two differently substituted pyrazole ligands have been investigated with regard to the topology of their Pt complexes: upon deprotonation, two mononuclear 1:2 PtII-pyrazole complexes—one sterically unhindered 4-Me-pzH and one bulky 3,5-tBu-pzH (pzH = pyrazole)—yield corresponding PtII-pyrazolato species; former a triangular, trinuclear metallacycle (1), latter dinuclear, half-lantern species (2...

2013
Poonam Khloya Pawan Kumar Arpana Mittal Neeraj K Aggarwal Pawan K Sharma

BACKGROUND Pyrazole and pyrazolone motifs are well known for their wide range of biological activities such as antimicrobial, anti-inflammatory, and antitumor activities. The incorporation of more than one pharmacophore in a single scaffold is a well known approach for the development of more potent drugs. In the present investigation, a series of differently substituted 4-arylidene pyrazole de...

2017
Ahmed A. Elhenawy

The present review covers the recent synthetic amino acid derivatives with chemical transformations to peptide derivatives. The amino acids were used as starting keys for synthesis peptides and pseudopeptides derived from pyridinine, coumarine, imaddizole, pyrazole phthalyl, qunolinine and sulfonamide rings. these biomolecules have diverse biological and pharmacological actions, as antimicrobia...

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