a, ar-Di(glycylamino)propionic acid hydrochloride, (NH&H2CONH)2C(CH,)COOH.HCl, is enzymatically hydrolyzed in aqueous extracts of rat kidney to yield, as a maximum, 1 mole of ammonia and 1 mole of pyruvic acid per mole of substrate (1). a-(dl-Chloropropionylamino)-a-(nI,-alanylamino)propionic acid and a:, ac-di(nL-alanylamino)propionic acid hydrochloride are also hydrolyzed by rat kidney, the f...

A mutation (modD) was selected in a gene involved in the control of protoplasmic incompatibility. Previous results (Labarere and Bernet 1979) showed that modD decreased the density of protoperithecia and caused a defect in ascospore germination. In addition, modD has a third defect: when modD stationary cells were isolated in order to obtain further development, renewal of growth rarely ensued....

Carbox dioxide fixation studies were conducted with rapidly growing JA-1 sarcoma cells in vitro. Isotope was isolated in asparagine, aspartic acid, glutamic acid, and glutamine. Chemical degradation of these compounds suggested three sites of fixation. They were carbon dioxide condensation with (a) pyruvic acid, (6) propionyl CoA, and (c) a three-carbon fragment such as the isopropyl carbons of...