An adynamic bone disorder (ABD) is an important complication of chronic kidney disease (CKD) of unknown etiology for which there is no adequate treatment. Reported is an animal model of ablative CKD complicated by an ABD characterized by the absence of secondary hyperparathyroidism and its successful treatment with a skeletal anabolic factor, bone morphogenetic protein-7 (BMP-7). Adult mice wer...

A fundamental question in biology is how complex structures are maintained after their initial specification. We address this question by reviewing the role of the Hox gene Abd-B in Drosophila testis organogenesis, which proceeds through embryonic, larval and pupal stages to reach maturation in adult stages. The data presented in this review highlight a cell- and stage-specific function of Abd-...

We present the SC-ABD algorithm that implements sequentially consistent distributed shared memory (DSM). The algorithm tolerates that less than half of the processes are faulty (crash-stop). Compared to the multi-writer ABD algorithm, SC-ABD requires one instead of two round-trips of communication to perform a write operation, and an equal number of round-trips (two) to perform a read operation...

The article is devoted to the history of coming power and analysis domestic foreign policy President Arab Republic Egypt (ARE), Field Marshal Abd-аl Fattah al-Sisi. author notes that new leader country chose a tough internal political course aimed at strengthening his own suppressing opposition, fi rst all, Muslim Brotherhood (the organization’s activities are prohibited on territory Russian Fe...

Plectin is a major component of the cytoskeleton and links the intermediate filament system to hemidesmosomes by binding to the integrin beta4 subunit. Previously, a binding site for beta4 was mapped on the actin-binding domain (ABD) of plectin and binding of beta4 and F-actin to plectin was shown to be mutually exclusive. Here we show that only the ABDs of plectin and dystonin bind to beta4, w...

Assurance Based Development (ABD) is a novel approach to the synergistic construction of critical software systems and their assurance arguments. In ABD, the need for assurance drives a unique process synthesis mechanism that results in a detailed operational process for building both software and an argument demonstrating its fitness for use in given operating contexts. In this paper, we intro...

W model a situation in which two retailers consider launching an “Advance Booking Discount” (ABD) program. In this program, customers are enticed to precommit their orders at a discount price prior to the regular selling season. However, these precommitted orders are filled during the selling season. While the ABD program enables the retailers to lock in a portion of the customer demand and use...