A simple, highly sensitive, accurate and selective method for determination of trace amounts of Ni2+ in water samples. In this paper, Dioctylphthalate (DOP) was used to encapsulate nano-Fe3O4 and produce a nano-Fe3O4-DOP sorbent based new sorbent was prepared. This was treated with ethylenediamine (ED) in another solvent-free procedure for the formation of a novel nano-Fe3O4-DOP-ED. Flame atomi...

Cloud point extraction (CPE) as a rapid, simple and efficient method coupled with high performance liquid chromatography (HPLC) was used for sample preparation and subsequent determination of carbazole, trinitrocarbazole (TrNC) and tetra nitro carbazole (TNC) in water samples. Some effective parameters on extraction, such as volume of Triton X-100, extraction time, extraction temperature, ionic...

A simple and reproducible HPLC method with spectrophotometric detection was developed for determination of rivastigmine in human plasma. Liquid-liquid extraction of rivastigmine and donepezil (as internal standard) from plasma samples was performed with 1-butanol/n-hexane (2:98 v/v) in alkaline condition followed by back-extraction into diluted acetic acid. Chromatography was carried out using ...

   In chiral and non-chiral electrophoretic resolution of basic drugs, adsorption of analytes to negatively charged capillary wall could lead to poor repeatability of migration time and peak area. In addition, chiral resolutions of basic drugs are commonly performed in low pH buffers. Therefore, longer analysis time due to suppression of electroosmotic flow (EOF) is another dilemma. In this wor...

A simple, rapid, and ultra sensitive dispersive solid phase extraction based on nano graphene oxide was developed for simultaneous measurement of trace amounts of metformin (MET) and linagliptin (LIN) in plasma samples by HPLC-UV-Vis. Affecting factors on the extraction of these drugs, including adsorbent weight, extraction time, organic solvent type, desorption situations, and composition of s...

Background: Honey has a lot of reputation because of its supposed medicinal properties. In this study, Hydroxymethylfurfural (HMF), sugars, and Fructose/Glucose ratio of honey in Bangladesh were assessed for adulteration and authenticity evaluation. Methods: Seventy honey samples collected from different districts of Bangladesh were analyzed by High Performance Liquid Chromatography (HPLC) for...

A method for the analysis of trace-level benzalkonium chloride has been established using flow injection ionspray mass spectrometry-mass spectrometry with multiple reaction monitoring. Quantification was carried out using an external standard based on peak area summation of each benzalkonium ion (C8, C10, C12, C14, C16 and C18) in the mass spectra. The multiple reaction monitoring technique pro...

A simple, sensitive and reliable method is described for simultaneous quantification of Carvedilol and its metabolite 4-Hydroxyphenyl Carvedilol in human plasma by using High-throughput liquid Chromatography–tandem mass spectrometric method. The method was carried out by on-line coupling of extraction with Cyclone P (50 mm × 0.5 mm 50 μm) HTLC(High-throughput liquid Chromatography) column by in...

A real-time PCR-based analytical method was developed for the event-specific quantification of a genetically modified (GM) soybean event, MON87701. First, a standard plasmid for MON87701 quantification was constructed. The conversion factor (Cf) required to calculate the amount of genetically modified organism (GMO) was experimentally determined for a real-time PCR instrument. The determined Cf...

Positron emission tomography (PET) is used extensively in clinical oncology for tumor detection, staging and therapy response assessment. Quantitative measurements of tumor uptake, usually in the form of standardized uptake values (SUVs), have enhanced or replaced qualitative interpretation. In this paper we review the current status of tumor quantification methods and their applications to cli...