The primary associations of the HLA class II genes, HLA-DRB1 and HLA-DQB1, and the class I genes, HLA-A and HLA-B, with type 1 diabetes (T1D) are well established. However, the role of polymorphism at the HLA-DRB3, HLA-DRB4, and HLA-DRB5 loci remains unclear. In two separate studies, one of 500 subjects and 500 control subjects and one of 366 DRB1*03:01-positive samples from selected multiplex ...

MATERIAL AND METHODS This cross-sectional study included 91 patients with stable CAD who had been under optimized cardiovascular care. Blood levels of IL-1β, IL-6, IL-8, IL-10, IFN-γ, and TNF-α were measured by Luminex technology. A full-mouth periodontal examination was conducted to record probing depth (PD) and clinical attachment (CA) loss. Multiple linear regression models, adjusting for ge...

Any configuration of lattice vectors gives rise to a hierarchy of higher-dimensional configurations which generalize the Lawrence construction in geometric combinatorics. We prove finiteness results for the Markov bases, Graver bases and face posets of these configurations, and we discuss applications to the statistical theory of log-linear models.

Atmospheric particulate matters were collected on quartz fibre filters for 24 hours with a low volume sampler from January 2014 to March 2014 at the Southeast Asian mega city (Dhaka, Bangladesh). Particulate matters samples were analysed for eleven trace metals with inductively coupled plasma mass spectrometer (ICP-MS) at Cà Foscari University of Venice, Italy. Trace metals were extracted from ...

Authotrophic denitrification with sulphide using nitrate (R1) and nitrite (R2) as electron acceptor were investigated at bench scale. Different SRT (5 and 20 d) have been tested in R1 while R2 was operated at SRT = 13 d. The results indicated that the process allows to achieve complete sulphide removal in all testes conditions. Tested sulphide loads were estimated form the H2S produced in a pil...

Although iron overload is clinically significant, only limited data have been published on iron overload in haematological diseases. We investigated cardiac and liver iron accumulation by magnetic resonance imaging (MRI) in a cohort of 87 subjects who did not receive chelation, including 59 haematological patients. M-HIC (MRI-based hepatic iron concentration, normal values <36 μmol/g) is a non-...

The role of genetic variation at the 3' end of the apolipoprotein B gene locus in the development of coronary heart disease and the regulation of the serum levels of various lipoproteins was studied by using two common restriction fragment length polymorphisms detected with the enzymes Xba I and EcoR I. A group of 106 male patients with coronary heart disease and 118 matched controls of Austria...

The role of multiple gonadotropin-releasing hormone receptor (GnRH-R) types in the regulation of gonadotropic and nongonadotropic cells remains speculative. To address this issue, we developed a technology integrating laser-captured microdissection of single digoxigenin-labeled pituitary cells coupled with real-time quantitative PCR to examine the expression profiles of three endogenous GnRH-R ...

INTRODUCTION The objective was to investigate associations between the HLA-A gene and Behcet's disease (BD) and its clinical manifestations. METHODS Genotyping for the HLA-A locus was performed using the polymerase chain reaction-Luminex typing method in 223 BD patients and 1,398 healthy controls. RESULTS The phenotypic frequencies of HLA-A*02:07 (odds ratio (OR) = 2.03, P = 0.002), A*26:01...

The aim of this study was to develop regression equations for stature estimation using the upper limb bone in Korean individuals. A total of 105 samples (55 men and 50 women) obtained from cadavers were used for developing equations. Bones with obvious pathologies or healed fractures were excluded. The coefficient of determination (r2) of the variables was slightly higher in men than in women. ...