In China, rabies is a significant public health concern where dogs remain the main reservoir of disease transmission to humans; rabies-related mortality ranks second in the world.We compiled all published articles and official documents on rabies in mainland China to examine challenges and needs to eliminate rabies in the country. The Chinese authorities have identified rabies as a priority, re...

INTRODUCTION Rabies is an acute fatal viral disease that is generally transmitted from animals to humans following wild and domestic animal bites. The rabies virus enters the body from the area where the individual is bitten, and then the virus moves towards the brain and involves the nerves. CASE PRESENTATION During the years 2001-2011, there have been 73 reported rabies cases. About 50,000 ...

Rabies is a reemerging and fatal infectious disease in Asia mainly caused by exposure to rabid dogs. The disease is transmitted through the bite of an infected animal, usually from a dog, and can be prevented by the timely administration of rabies immune globulins and post-bite vaccination. Prevention of dog rabies would be the most effective way to stop rabies transmission to humans. However, ...

Although Indonesia has been rabies-infected since at least the 1880s, some islands remain rabies-free, such as Lombok. However, due to its adjacency to rabies-infected islands such as Bali and Flores, there is considerable risk of a rabies incursion. As part of a rabies risk assessment project, surveys were conducted to estimate the size of the dog population and to describe dog management prac...

Canine rabies is enzootic throughout Sub-Saharan Africa, including the Republic of South Africa. Historically, in South Africa the coastal provinces of KwaZulu-Natal and Eastern Cape were most affected. Alarmingly, outbreaks of canine rabies have been increasingly reported in the past decade from sites where it has previously been under control. From January 2010 to December 2011, 53 animal rab...

Rabies a zoonotic disease prevalent worldwide, with high mortality, more than a third of global toll in India. Dogs are the common animals involved. In Americas, bat bites are the most common source of rabies infection in humans. Rabies is caused by lyssaviruses including rabies virus and Australian bat lyssavirus. Disease produces almost fatal encephalitis in humans and in other mammals. From ...

Rabies is a lethal form of encephalitis and enzootic in many parts of Asia and Africa where it poses a significant veterinary and public health concern [1,2]. Rabies is caused by neurotropic viruses of the genus Lyssavirus. It is a zoonotic infection mainly transmitted through the saliva of infected animal. Extensive efforts in developed countries (America and Europe) have largely controlled do...

Rabies virus causes lethal brain infection in about 61000 people per year. Each year, tens of thousands of people receive anti-rabies prophylaxis with plasma-derived immunoglobulins and vaccine soon after exposure. Anti-rabies immunoglobulins are however expensive and have limited availability. VHH are the smallest antigen-binding functional fragments of camelid heavy chain antibodies, also cal...

INTRODUCTION In the continental US, four terrestrial mammalian species are reservoirs for seven antigenic rabies virus variants. Cross species transmission (CST) occurs when a rabies virus variant causes disease in non-reservoir species. METHODS This study analyzed national surveillance data for rabies in terrestrial mammals. The CST rate was defined as: number of rabid non-reservoir animals/...

BACKGROUND Rabies is a fatal viral disease that continues to threaten both human and animal health in endemic countries. The Lao People's Democratic Republic (Lao PDR) is a rabies-endemic country in which dogs are the main reservoir and continue to present health risks for both human and animals throughout the country. METHODS Passive, laboratory-based rabies surveillance was performed for su...