background: quantification of radiation-induced apoptosis in peripheral blood lymphocytes (pbls) has been proposed as a possible screening test for cancer-prone individuals and also for the prediction of normal tissue responses after radiotherapy. materials and methods: the neutral version of the comet assay (single-cell gel electrophoresis) was used 24, 48, 72 hours after irradiation with 8 gy...

Introduction: Alveolar soft part sarcoma is a very rare and aggressive type of sarcoma. Although its histology genetic characteristics have been identified, the benefits adjuvant radiotherapy for treatment are still being studied. Case presentation: In November 2007, 21-year-old woman presented with primary tumor in right thigh, histological immunohistochemical confirmation an alveolar sarcoma,...

BACKGROUND Cancer control by radiotherapy (RT) can be improved with concurrent chemotherapy. Outpatient strategies for sarcomas that combine chemotherapy and RT are possible since supportive care and RT techniques have improved. METHODS The current status of non-anthracycline chemotherapy in combination with radiation for high-risk sarcoma is reviewed. RESULTS Ifosfamide with mesna and newe...

BACKGROUND Classic Kaposi's sarcoma is a lymphatic endothelial cell neoplasm usually present on the skin of the upper and lower extremities. Although it commonly affects human immunodeficiency virus positive patients, there have been some human immunodeficiency virus negative cases reported. We report an uncommon presentation of stage IV classic Kaposi's sarcoma in an human immunodeficiency vir...

PET/MRI is an evolving hybrid imaging modality which combines the inherent strengths of MRIs soft-tissue and contrast resolution and PETs functional metabolic capabilities. Bone and soft-tissue sarcoma are a relatively rare tumor entity, relying on MRI for local staging and often on PET/CT for lymph node involvement and metastatic spread evaluation. The purpose of this article is to demonstrate...

The synovial sarcoma of the larynx is a very rare tumour. Only six cases have been published so far in international literature. We describe a synovial sarcoma of the larynx in a 53-year old patient. Laryngectomy and neck-dissection were performed, followed by adjuvant radiotherapy. 16 months after therapy neither locoregional recurrence nor lung metastases have occurred. Clinically, an attempt...

A patient with uveitis and retinal pigment epithelial detachments underwent an extensive medical examination and pars plana vitrectomy in an attempt to confirm the clinical diagnosis of reticulum cell sarcoma. None of these examinations revealed the presence of malignancy. Transscleral biopsy of subretinal lesions confirmed the histopathological diagnosis of reticulum cell sarcoma. The patient ...

A patient with uveitis and retinal pigment epithelial detachments underwent an extensive medical examination and pars plana vitrectomy in an attempt to confirm the clinical diagnosis of reticulum cell sarcoma. None of these examinations revealed the presence of malignancy. Transscleral biopsy of subretinal lesions confirmed the histopathological diagnosis of reticulum cell sarcoma. The patient ...

Background: Ionizing radiation induces the production of reactive oxygen species (ROS), which play an important causative role in cell death. Wholebody exposure of mice to gamma radiation leads to diminution of tissue antioxidant defense systems increases the peroxidative damage to membrane lipids and damages the haematopoietic and gastrointestinal systems. Tempol (TPL), a cell membranep...

AIM The aim of this retrospective study was to investigate the clinical and histopathological characteristics of the disease and treatment outcome of patients with pure uterine sarcomas. BACKGROUND Uterine sarcomas are especially rare tumours, comprising only 3-5% of uterine cancers. They are characterized by histopathological diversity, rapid clinical progression, and poor prognosis. Optimal...