BACKGROUND Radiation exposure can lead to detrimental effects in skin microcirculation. The precise relationship between radiation dose received and its effect on cutaneous perfusion still remains controversial. Previously, we have shown that hyperspectral imaging (HSI) is able to demonstrate long-term reductions in cutaneous perfusion secondary to chronic microvascular injury. This study chara...

introduction: radiation induced bystander effect (ribe) which cause radiation effects in non-irradiated cells, has challenged the principle according to which radiation traversal through the nucleus of a cell is necessary for producing biological responses. what is the mechanism of this phenomenon? to have a better understanding of this rather ambiguous concept substantial number of original an...

background: the number of interventional cardiology (ic) procedures has increased rapidly. coronary angiography (ca) and percutaneous transluminal coronary angioplasty (ptca) are now widely performed as a matter of routine, and they are considered safe procedures for experienced cardiologists. however, it is also known that these procedures are associated with high radiation doses due to long f...

Accidental or deliberate ionizing radiation exposure can be fatal due to widespread hematopoietic destruction. However, little is known about either the course of injury or the molecular pathways that regulate the subsequent regenerative response. Here we show that the Wnt signaling pathway is critically important for regeneration after radiation-induced injury. Using Wnt reporter mice, we show...

Dose escalation is now the standard of care for the treatment of prostate cancer with radiation therapy. However, the rectum tends to be the dose-limiting structure when treating prostate cancer, given its close proximity. Early and late toxicities can occur when the rectum receives large doses of radiation therapy. New technologies allow for prevention of these toxicities. In this review, we e...

According to the International Atomic Energy Agency (IAEA), a relatively significant number of radiological accidents have occurred in recent years mainly because of the practices referred to as potentially high-risk activities, such as radiotherapy, large irradiators and industrial radiography, especially in gammagraphy assays. In some instances, severe injuries have occurred in exposed person...

Radiation gastritis has rarely been reported [1]. In this study, radiation gastritis was defined on endoscopy as a red lesion, usually larger than 2cm, that was sharply demarcated from the surrounding normal mucosa, and was found in a focal area of the stomach when erosive gastritis had been excluded. Overall, 31 patients were diagnosed as having radiation gastritis. Of these, 22, 13, and 3 als...

acute injuries of the spine and spinal cord are among the most causes of severe disability and death after trauma. data about spine fracture with or without cord damage are different. the aim of this study was to determine epidemiology and demographics of spinal injury in main trauma center, guilan, an iranian province. the present study was a descriptive study of all cases of traumatic spine i...