Medulloblastoma is a rare brain malignancy. Patients after puberty are and bear an intermediate prognosis. Standard treatment consists of maximal resection plus radio-chemotherapy. Treatment toxicity high produces disabling long-term side effects. The sonic hedgehog (SHH) subgroup highly overrepresented in the post-pubertal adult population can be targeted by smoothened (SMO) inhibitors. No pra...

This paper proposes a Radio Resource Management strategy for unidirectional satellite systems delivering multicast and broadcast services to mobile users. Both the radio interface and the targeted services impose particular requirements on the RRM task. We present the individual RRM entities, describe their exact role and suggest algorithms for their functions.

An overview of software radio and reconfigurable radio is given, with a special emphasis on results from EU-funded projects. The state-of-the art in reconfigurable radio is presented, detailing architectures providing reconfigurability for networks and services. The allsoftware approach for reconfigurable network elements and terminals is described. Finally, the Eurecom software radio platform ...

We investigate the radio emission of ∼ 185,000 quiescent (optically unclassifiable) galaxies selected from the Sloan Digital Sky Survey (SDSS). By median-stacking FIRST cutouts centered on the optically-selected sources, we are able to reach flux densities down to the 10s of μJy. The quiescent galaxy sample is composed of two subgroups inhabiting vastly different regimes: those targeted for the...

background human telomerase reverse transcriptase (htert) has become an ideal target for development of anticancer therapy. small interfering rnas (sirnas) are very powerful reagents for gene silencing and show promise for cancer gene therapy. however, only a small number of sirnas have been demonstrated to be effective. for gene therapy targeting htert, it is essential to develop a robust syst...

BACKGROUND Colorectal cancer (CRC) is one of the most common cancers all over the world, but its epidemiology is obviously different in various regions. METHODS The treatment of CRC also has varying characteristics due to differences in economy, geography, disease onset, chemotherapy, and other factors, although international guidelines are used to guide the treatment of CRC in China. RESUL...

Several treatment options, including endocrine therapy, chemotherapy, and targeted therapy, have been shown to improve survival of breast cancer patients. Currently, clinical tests for predicting cancer response are not available, and individual markers have shown little predictive value. Several gene expression profiling studies have been carried out in the attempt to identify predictive signa...

introduction: there is a limited number of case reports published in the past decade confirming the radio-iodine presence in the tear. these observations as well as reported cases of salivary and lacrimal gland dysfunction after radioiodine therapy stimulated investigators to clarify whether lacrimal gland function can be affected post-radioiodine therapy. hence we planned a historical cohort s...

Introduction: To increase the radiation therapy efficiency, two approaches have been employed which include increasing the dose delivery or modifying the biological response to ionizing radiation. This study aimed to modify the biological response to ionizing radiation by combination therapy using radio-sensitizer agent and anticancer drug. Materials and Methods:</str...