نتایج جستجو برای: radioactive i 123

تعداد نتایج: 1072348  

Journal: :Movement disorders : official journal of the Movement Disorder Society 2008
Angelo Antonini Patrizia Berto Stefania Lopatriello Filippo Tamma Lieven Annemans Mike Chambers

Economic evaluation (Italian NHS perspective) modeling (123)I-FP-CIT SPECT (DaTSCAN) compared to clinical judgment alone for differentiating essential tremor (ET) from Parkinson's Disease (PD). A 5-year Markov model was constructed to assess the cost-effectiveness of (123)I-FP-CIT SPECT to differentiate ET from PD in patients referred to a movement disorder specialist in Italy. Published data a...

Radioiodinated meta iodobenzylguanidine (MIBG) is one of the important radiopharmaceuticals in Nuclear Medicine. [123/131I]MIBG is used for imaging of Adrenal medulla, studying heart sympathetic nerves, treatment of pheochromacytoma and neuroblastoma. For clinical application, radioiodinated MIBG is prepared through isotopic exchange method, which includes replacement of radioactive iodine in a...

Journal: :Circulation research 2016
Valentina Parisi Giuseppe Rengo Pasquale Perrone-Filardi Gennaro Pagano Grazia Daniela Femminella Stefania Paolillo Laura Petraglia Giuseppina Gambino Aurelio Caruso Maria Gabriella Grimaldi Francesco Baldascino Maria Nolano Andrea Elia Alessandro Cannavo Antonio De Bellis Enrico Coscioni Teresa Pellegrino Alberto Cuocolo Nicola Ferrara Dario Leosco

RATIONALE It has been reported that epicardial adipose tissue (EAT) may affect myocardial autonomic function. OBJECTIVE The aim of this study was to explore the relationship between EAT and cardiac sympathetic nerve activity in patients with heart failure. METHODS AND RESULTS In 110 patients with systolic heart failure, we evaluated the correlation between echocardiographic EAT thickness an...

Journal: :European heart journal 2007
Shu Kasama Takuji Toyama Takashi Hatori Hiroyuki Sumino Hisao Kumakura Yoshiaki Takayama Shuichi Ichikawa Tadashi Suzuki Masahiko Kurabayashi

AIMS It has been reported that carvedilol improves cardiac sympathetic nerve activity (CSNA) in patients with dilated cardiomyopathy (DCM). However, the influence of carvedilol on cardiac (123)I-meta-iodobenzylguanidine (MIBG) scintigraphic findings and left ventricular (LV) remodelling has not been determined in DCM patients. METHODS AND RESULTS In 30 patients with DCM and 10 normal controls...

Journal: :Progress in medicinal chemistry 2000
V W Pike C Halldin H V Wikström

[Carbonyl-(11)C]WAY-100635 (WAY) has proved to be a very useful radioligand for the imaging of brain 5-HT(1A) receptors in human brain in vivo with positron emission tomography (PET). WAY is now being applied widely for clinical research and drug development. However, WAY is rapidly cleared from plasma and is also rapidly metabolised. A comparable radioligand, with a higher and more sustained d...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008
Hiroki Kato Eku Shimosegawa Naohiko Oku Kazuo Kitagawa Haruhiko Kishima Youichi Saitoh Amami Kato Toshiki Yoshimine Jun Hatazawa

UNLABELLED (123)I-Iomazenil brain SPECT has been used for the detection of epileptogenic foci, especially when surgical intervention is considered. Although epileptogenic foci exhibit a decrease in (123)I-iomazenil accumulation, normal cerebral cortices often exhibit similar findings because of thin cortical ribbons, gray matter atrophy, or pathologic brain structures. In the present study, we ...

Journal: :Chest 1999
F Sakamaki T Satoh N Nagaya S Kyotani N Nakanishi Y Ishida

BACKGROUND Cardiac and systemic autonomic nervous function may be impaired in patients with COPD. Few reports, however, have described sympathetic nervous function of the left ventricle (LV) in COPD patients. STUDY OBJECTIVE To assess the LV sympathetic nervous function in patients with COPD using (123)I-metaiodobenzylguanidine (MIBG) imaging of the heart. DESIGN Prospective comparison of (...

Journal: :Heart 2011
Shu Kasama Takuji Toyama Hiroyuki Sumino Hisao Kumakura Yoshiaki Takayama Kazutomo Minami Shuichi Ichikawa Naoya Matsumoto Yuichi Sato Masahiko Kurabayashi

BACKGROUND Many studies have shown that cardiac sympathetic nerve activity evaluated by [(123)I]m-iodobenzylguanidine ([(123)I]MIBG) scintigraphic study during a stable period is useful for determining the prognosis of patients with chronic heart failure. OBJECTIVE To examine whether results of this imaging method performed 3 weeks after the onset of ST-segment elevation myocardial infarction...

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