Radium 223 is an alpha-emitting intravenous radiotherapy approved for the treatment of men with metastatic castration-resistant prostate cancer (mCRPC). The approved indication covers men with pain from bony metastatic disease and no visceral involvement; however, questions remain as to optimal patient selection and timing of this treatment relative to other life-extending therapies for mCRPC. ...

Radium 223 is an alpha-emitting intravenous radiotherapy approved for the treatment of men with metastatic castration-resistant prostate cancer (mCRPC). The approved indication covers men with pain from bony metastatic disease and no visceral involvement; however, questions remain as to optimal patient selection and timing of this treatment relative to other life-extending therapies for mCRPC. ...

The requirements on a neutral current additive tc the heavy water in the SNO project are as follows: water solubility, low inherent radioactivity or the availability of an easy path of purification from thorium and radium, the possibility for easy separation from the water phase and safety. The solution of such an additive is expected to be transparent in the visible range, stable for extended ...

1 Department of Informatics, University of Oslo, Blindern, Oslo, Norway, 2 Centre for Cancer Biomedicine, University of Oslo, Blindern, Oslo, Norway, 3 Department of Biochemistry and Molecular Biology and The Huck Institutes for the Life Sciences, Penn State University, University Park, Pennsylvania, United States of America, 4 Department of Biology and Department of Mathematics and Computer Sc...

Several papers [1, 2, 3) 2 and Handbooks [4, 5] have been published during the past 20 years dealing with barrier req uirements for shielding against gamma radiation from radium. These publications have usually suggested lead for the barriers because a large proportion of the applications required restricted space and ready transportabi lity of the barrier and gamma-ray source. For h igh-energy...

OBJECTIVES/HYPOTHESIS Nonchordomatous lesions of the clivus are rare entities. Nasopharyngeal radium irradiation (NRI) treatment consists of application of radium to the posterior nasopharynx near the orifice of the Eustachian tubes, an area adjacent to the clivus. Here we present a unique case of a patient with a history of NRI 70 years prior to presentation with a space-occupying clival lesio...

Cyst is a pathological cavity filled with fluid, semifluid or gaseous content lined by epithelium and not created the accumulation of pus. Cysts jaws are treated enucleation marsupialization. After removal cyst, space-occupying stent fabricated for faster healing patient comfort. Stents appliances constructed to cover tissues teeth their protection, carry medicaments, radium material, control b...

Haemangiomas are benign skin lesions that usually regress spontaneously, but radiotherapy has previously been used to assist the regression and healing of the lesions. Radium and X-rays were used as a treatment for benign skin lesions such as haemangioma until the carcinogenic effect of ionising radiation in humans was described. We report a patient diagnosed with a sarcomatoid carcinoma. Her p...

The objective: is to determine the current role of radium-223 in emergence new options treatment patients with metastatic castration-resistant prostate cancer.
 Materials and methods. Studies ERA-223 ALSYMPCA have identified cancer its impact on human health.
 Results. In one such study, ERA-223, it was shown that combination abiraterone did not increase survival without symptomatic s...