To the Editor: We would like to thank Moolgavkar et aP for their provocative and informative article on lung cancer and its relation to radon exposure and cigarette smoke. Their observations supporting a two-mutation model for both tobacco and radon may help to explain some of the confusing observations regarding respirable crystalline silica, . tobacco smoke, and the development of pulmonary n...

BACKGROUND In contrast with established evidence linking high doses of ionizing radiation with childhood cancer, research on low-dose ionizing radiation and childhood cancer has produced inconsistent results. OBJECTIVE We investigated the association between domestic radon exposure and childhood cancers, particularly leukemia and central nervous system (CNS) tumors. METHODS We conducted a n...

BACKGROUND Radon and its decay products, a source of ionizing radiation, are primarily inhaled and can deliver a radiation dose to breast tissue, where they may continue to decay and emit DNA damage-inducing particles. Few studies have examined the relationship between radon and breast cancer. METHODS The Nurses' Health Study II (NHSII) includes U.S. female registered nurses who completed bie...

background: the potential hazards of exposure to radiation from radon have been of great concern worldwide, as it is associated with an increased risk of lung cancer. radon (222rn) and its progeny are the main sources of radioactivity in the environment. the half-life of 222rn (3.82 days) is long enough for it to diffuse into and build up in homes. 220rn or thoron from the 232th series, and 219...

Cohort mortality studies of underground miners have been used to estimate the number of lung cancer deaths attributable to radon exposure. However, previous studies of the radon-lung cancer association among underground miners may have been subject to healthy worker survivor bias, a type of time-varying confounding by employment status. We examined radon-mortality associations in a study of 4,1...

In most countries, radon is the dominant contributor among natural radiation sources to the radiation exposure dose of the general population. Numerous case-control studies of residential radon and lung cancer have been conducted using passive radon (Rn-222) detectors. These studies showed that radon may increase lung cancer risk, but most of them did not show a significant risk. Recently it wa...

The indoor radon program in the US. started in the early 1970's in response to Congressional Hearings that recommended the initiation of radon measurements in certain parts of the united States where enhanced radon caused by contaminated uranium and radium tailings was suspect. In the mid 1970's, the Department of Energy (DOE), Environmental Measurements Laboratory (EML), conducted the first in...

The literature proves an evident association between indoor radon exposure and lung cancer, even at low doses. This study brings a new approach to the study of children's exposure to radon by aiming to evaluate exposure to indoor radon concentrations in nursery and primary schools from two districts in Portugal (Porto and Bragança), considering different influencing factors (occupation patterns...

A case-control study based on interviews with 210 incident female lung cancer patients, 209 age-matched population controls, and 191 hospital controls was carried out in Stockholm county, Sweden. Radon measurements made in a sample of 303 dwellings, in which the study subjects had lived, showed that dwellings with ground contact had an average concentration of approximately 160 Bqm-3, twice the...

The large United States county-based study () in which an inverse relationship has been suggested between residential low-dose radon levels and lung cancer mortality has been reviewed. While this study has been used to evaluate the validity of the linear nonthreshold theory, the grouped nature of its data limits the usefulness of this application. Our assessment of the study's approach, includi...