Renin and aldosterone secretion is often lower in blacks than in whites, characteristics that resemble a milder form of Liddle syndrome in which a mutation in the amiloride-sensitive epithelial sodium channel (ENaC) of the kidney results in enhanced resorption of sodium. In the present study, we looked for evidence that the intrinsic level of ENaC activity is indeed higher in blacks than in whi...

Fig. 2: a) Na MRI of a healthy human brain (Hamming filter). b) Before the calculation of the Cl/Na ratio maps, the Na MRI data was reconstructed with a Gaussian filter (b) to achieve the similar actual spatial resolution than in Cl MRI (c). d) Calculated Cl/Na ratio maps of the healthy human brain. Fig. 3: Glioblastoma patient. a) Contrastenhanced T1-weighted MPRAGE image (B0=3T). b) Cl /Na ra...

The physiological responses of silicate-based bioactive glasses (BGs) are known to depend critically on both the P content (n(P)) of the glass and its silicate network connectivity (N(BO)(Si)). However, while the bioactivity generally displays a nonmonotonic dependence on nP itself, recent work suggest that it is merely the net orthophosphate content that directly links to the bioactivity. We e...

We investigate the potential of multiple quantum filtered (MQF) (23)Na NMR to probe intracellular [Na]i in the Langendorff perfused mouse heart. In the presence of Tm(DOTP) shift reagent the triple quantum filtered (TQF) signal originated largely from the intracellular sodium pool with a 32±6% contribution of the total TQF signal arising from extracellular sodium, whilst the rank 2 double-quant...

p-Type ZnO microwires were first synthesized by a simple chemical vapor deposition method using Na as the dopant source. p-Type doping was confirmed by the electrical transport in single-wire field-effect transistors and low-temperature photoluminescence. The carrier mobility of the microwires was estimated to be approximately 2.1 cm(2) V(-1) S(-1).

Recent studies demonstrated that in addition to Na+,K+-ATPase inhibition cardiotonic steroids (CTSs) affect diverse intracellular signaling pathways. This study examines the relative impact of [Na+]i/[K+]i-mediated and -independent signaling in transcriptomic changes triggered by the endogenous CTSs ouabain and marinobufagenin (MBG) in human umbilical vein endothelial cells (HUVEC). We noted th...

in wheat na+ exclusion and k+/na+ have shown to be associated with salinity tolerance, therefore in order to identify qtls with additive effect for na+ and k+ concentration traits in roots and shoots of wheat, 319  bread wheat recombinant inbred lines (ril f7), derived from a cross between roshan cultivar (salt tolerant) and falat cultivar (salt sensitive), along with their parents and 2 checks...

This thesis is written for the Swedish degree Licentiate of Science, teknisk licentiat. It is a university degree, intermediate between that of master and that of doctor. We study the approximability of different generalizations of the Max Cut problem. First, we show that Max Set Splitting and Max Not-All-Equal Sat are both approximable within 1.380 in probabilistic polynomial time. The algorit...