CADIAG-1 is a medical expert system, based on a symbolic logic representation of medical relationships. Strong relationships such as confirming, excluding or obligatory occurrence are applied to confirm or exclude diagnoses. Weak relationships are represented by facultative and not confirming relationships (FN-relationships). Diagnostic hypotheses are established by systematic combination of sy...

OBJECTIVE AI/RHEUM is a multimedia expert system developed originally to assist in the diagnosis of rheumatic diseases in adults. In the present study we evaluated the usefulness of a modified version of this diagnostic decision support system in diagnosing childhood rheumatic diseases. METHODOLOGY AI/RHEUM was modified by the addition of 5 new diseases to the knowledge base of the system. Cr...

Introduction. Most documented rare diseases have genetic origin. Because of their low individual frequency, an initial diagnosis based on phenotypic symptoms is not always easy, as practitioners might never have been exposed to patients suffering from the relevant disease. It is thus important to develop tools that facilitate symptom-based initial diagnosis of rare diseases by clinicians. In th...

we aimed to evaluate clinical, high resolution computed tomography (hrct) and pulmonary function test (pft) findings after 18-23 years of exposure in veterans of sulphur mustard (sm) exposure. we performed a cross-sectional study of 106 patients. inclusion criteria were 1: documented exposure to sm as confirmed by toxicological analysis of their urine and vesicular fluid after exposure 2: singl...

We have developed computer-aided diagnosis (CAD) schemes for the detection of lung nodules, interstitial lung diseases, interval changes, and asymmetric opacities, and also for the differential diagnosis of lung nodules and interstitial lung diseases on chest radiographs. Observer performance studies indicate clearly that radiologists' diagnostic accuracy was improved significantly when radiolo...

The design of a multi-functional fiber-based Optical Coherence Tomography (OCT) system for human retinal imaging with < 2 micron axial resolution in tissue is described. A detailed noise characterization of two supercontinuum light sources with different pulse repetition rates is presented. The higher repetition rate and lower noise source is found to enable a sensitivity of 96 dB with 0.15 mW ...

The incidence of dental fluorosis in Sudan ranges from 4.5–100% depending on the fluoride level in potable water. The present study was designed to determine the maximum safe level for fluoride in potable water under the conditions currently prevailing in the affected areas using the Galagan and Vermillion equation which permits the calculation of the upper permissible fluoride level as a funct...

This paper describes a study of surgical diagnosis assisted by a computer. The study was carried out in the University of Leeds, involved the Department of Surgery and the Centre for Computer Studies and made use of an English Electric KDF9 computer. A real-life real-time controlled trial was carried out on a consecutive unselected series of 552 further patients. This trial included all patient...