We have recently been able to improve the conditions for in vitro lymphocyte cultures such that every growth-inducible murine B cell, in the presence of a Bcell mitogen, will initiate growth and maturation to IgM-, IgG-, and IgAsecreting plaque-forming cells (PFC) (1, 2). 1 This was achieved mainly by adding 2-mercaptoethanol (3), a growth-supporting fetal calf serum (4), growthsupporting thymu...

A total of 74 COVID-19 diabetic patients were enrolled in the study. Twenty-seven (36.5%) severely ill, and ten (13.5%) died. Severe had higher blood glucose, serum amyloid (SAA), C reactive protein, interleukin 6 levels than non-severe (P> 0.05). lower albumin, cholesterol, high density lipoprotein, small dense low CD4 T lymphocyte counts (P > Reduced 21 + (OR = 0.988, 95 percent confide...

Objective: to evaluate CANLPH score and systemic immune inflammation index (SII) in patients with symptomatic rheumatic mitral stenosis (MS) undergoing percutaneous balloon valvuloplasty (PMBV). Methods: 62 who underwent PMBV our clinic between 2018 2021 were included retrospectively. The divided into 2 groups according echo score. was calculated from the cut-off values of C-reactive protein al...

Background: COVID-19 is a highly infectious disease that necessitates simple and rapid methods for recognising severe patients. Aims: To correlate between chest lesions in CT, neutrophil-lymphocyte ratio (NLR), platelets-lymphocytes patients with COVID-19, to detect their cut-off values as an early warning of Egyptian Subjects Methods: A cross-sectional study included 100 adult attending Ahmed ...

Background and objective: Coronavirus 2019 (COVID-19), first detected in patients Wuhan, China, soon became an international emergency concern. Since, blood tests can play a pivotal role the early diagnosis management present study aimed to investigate any possible association between hematological biochemical markers prognosis these patients. Methods: The was conducted 60 confirmed COVID-19 (3...

Relapse of chronic myeloid leukemia (CML) in chronic phase after allogeneic stem cell transplantation (SCT) can be successfully treated by donor lymphocyte infusion (DLI). However, relapse of accelerated phase CML, blast crisis, or acute leukemia after allogeneic SCT are resistant to DLI in the majority of cases. In vitro-selected and expanded leukemia-reactive T-cell lines may be more effectiv...

unresponsiveness to hepatitis b surface antigen (hbsag) has been shown to be associated with dysfunction of the presenting cells (apc) and defect in the specific b-lymphocyte and/or t-lymphocyte repertoires.   direct determination of the frequency of specific t-lymphocytes together with complementary analysis of the naive circulating immune cells could provide valuable information about the cel...

We have described a model system in which helper T cells are required to mount a primary antiviral cytolytic T lymphocyte response. The radioresistant helper cell can be found in the spleens of mice that have been immunized subcutaneously with influenza viruses 6-8 d previously. These helper cells appear to be type specific but cross-reactive among the subtypes of influenza A viruses. The pheno...

Annotation. Changes in the complete blood count (CBC) that were recorded patients against background of coronavirus infection (COVID-19) attracted attention many researchers from beginning pandemic, especially terms assessing prognosis, severity course disease a particular patient. It should be noted changes CBC can both reactive and systemic response or even reflect toxic effects this on bone ...

Introduction: Various inflammatory markers and laboratory parameters were identified as the predictors of severity mortality in COVID -19 infection. However, progression their gender difference COVID-19 deaths has not been extensively studied. The study aim was to analyze markers, neutrophil lymphocyte ratio (NLR), platelet (PLR) deaths, analyzed correlation between NLR, PLR markers. Materials ...