Background: According to the EAU guidelines, a life expectancy of more than 10 years is considered an important factor in the treatment of prostate cancer. The Charlson score is used to predict mortality based on comorbidies.The purpose of this study was to investigate the relationship between age, Charlson score and outcome in patients with cT3a prostate cancer. Materials and Methods: Between ...

External beam radiotherapy (EBRT) for the treatment of loco-regional prostate cancer yields similar survival rates to radical prostatectomy (10-year survival: 90-95%, 60-70% and 50-60% in T1, T2 and T3-stages, respectively). Post-operative radiotherapy in high-risk prostate cancer may improve the local and distant disease-free survival of patients. Using the recently developed technology of the...

We experienced 3 cases of manometry-induced colon perforation. A 75-year-old man (case 1) underwent anorectal manometry (ARM) 3 years after radiotherapy for prostate cancer and a laparoscopic intersphincteric resection for rectal cancer. A 70-year-old man (case 2) underwent ARM 3 months after conventional neoadjuvant chemoradiotherapy and a laparoscopic low anterior resection for rectal cancer....

Radiotherapy is an effective tool for the palliation of symptoms commonly caused by prostate cancer. The majority of painful bone metastases respond equally well to single or multiple fractions of external radiotherapy. Retreatment with a second course of radiation induces pain responses in approximately 50% of patients. For more diffuse metastases, either hemibody radiation or systemic radioph...

Radiotherapy is a commonly used, potentially curative treatment modality in patients with localised and locally advanced prostate cancer. The development of a radiation-induced second primary cancer is a serious long-term side effect of radiotherapy treatment. Prostate cancer is the most common cancer in males in the UK, with a lifetime risk of one in eight. Since the advent of prostate specifi...

PURPOSE Hypofractionated radiotherapy can reduce treatment durations and produce effects identical to those of conventionally fractionated radiotherapy for treating prostate cancer. Volumetric arc radiotherapy (VMAT) can decrease the treatment machine monitor units (MUs). Previous studies have shown that VMAT with multileaf collimator (MLC) rotation exhibits better target dose distribution. Thu...

We present the case report of a twenty-five-year-old Moroccan male patient who suffered from leptomeningeal carcinomatosis related to a signet-ring cell carcinoma of the rectum. He presented to the emergency department with abdominal pain, constipation, weight loss and rectal bleeding. The rectal examination showed a rectal tumor and a CT scan revealed a large bowel obstruction due to rectal di...

There is no consensus on the use of neoadjuvant radiotherapy for tumors upper third rectum. Due to conflicting findings in high-quality trials and significant long-term side effects associated with radiotherapy, benefit rectal less certain than lower two tumors. This metaanalysis compares oncological outcomes surgery versus alone PubMed, Embase, Cochrane library databases were searched. Randomi...

UNLABELLED Prostate adenocarcinomas present a high risk of metastasis. We report a case of an atypical prostate cancer metastasis. A male patient presented a prostatic adenocarcinoma treated by surgery. A biological recurrence was discovered during the follow-up by an increased rate of Prostate Specific Antigen (PSA) and was treated by hormonotherapy. Several months later, there was a re-increa...

background: stereotactic body radiotherapy (sbrt) has emerged as an effective treatment for localized prostate cancer. however, prostate-specific antigen (psa) kinetics after sbrt has not been well characterized. the objective of the current study is to analyze the rate of psa decline and psa nadir following hypofractonated sbrt in localized prostate cancer. materials and methods: from 2008 to ...