BACKGROUND Urinary tract infection (UTI) remains one of the main complications after kidney transplantation and it has serious consequences. METHODS Fifty-two patients with kidney transplantation were evaluated for UTI at 3-145 days (mean 40.0 days) after surgery.. Forty-two received a graft from a live donor and 10 from a deceased donor. There were 22 female and 30 male patients, aged 11-47 ...

Vaginal colonisation with E. coli appears to be an important prerequisite for the development of UTI. Whereas colonisation with P fimbriated strains has been clearly shown to predispose to pyelonephritis, virulence factors which predispose to cystitis have not been so clearly identified. Several host genetic and behavioural factors have been found to be associated with increased colonisation wi...

BACKGROUND Urinary tract infection (UTI) is common in spinal cord injured patients. The authors investigated the epidemiology of bacteria associated with UTI to select an appropriate antibiotic for empirical treatment of UTI before obtaining a bacterial culture. OBJECTIVE To determine the prevalence, as well as the causative bacteria and their susceptibility pattern of urinary tract infection...

OBJECTIVE To estimate the cost-effectiveness of a two-step clinical rule using symptoms, signs and dipstick testing to guide the diagnosis and antibiotic treatment of urinary tract infection (UTI) in acutely unwell young children presenting to primary care. METHODS Decision analytic model synthesising data from a multicentre, prospective cohort study (DUTY) and the wider literature to estimat...

UNLABELLED 1. Evaluating and treating bladder and bowel dysfunction are critical in reducing the risk of urinary tract infections (UTIs). 2. The pathogenesis of Escherichia coli infections reveals that quiescent intracellular reservoirs may be antibiotic-protected sources of recurrent infections. OBJECTIVES 1. Review the documentation of UTI and the importance of the urine culture. 2. Underst...

Uropathogenic E. coli (UPEC) is the primary cause of urinary tract infections (UTI) affecting approximately 150 million people worldwide. Here, we revealed the importance of transcriptional regulator hypoxia-inducible factor-1 α subunit (HIF-1α) in innate defense against UPEC-mediated UTI. The effects of AKB-4924, a HIF-1α stabilizing agent, were studied using human uroepithelial cells (5637) a...

BACKGROUND AND OBJECTIVES Renal transplantation is increasingly performed in elderly patients, and the incidence of benign prostatic hyperplasia (BPH) increases with age. Anuric males on dialysis may have occult BPH and not develop obstructive symptoms until urine flow is restored after transplantation. If left untreated, BPH poses a risk for numerous complications, including acute urinary rete...

PURPOSE Urinary stasis is a risk factor for recurrent urinary tract infection (UTI). Homozygous mutant Megabladder (Mgb-/-) mice exhibit incomplete bladder emptying as a consequence of congenital detrusor aplasia. We hypothesize that this predisposes Mgb-/- mice to spontaneous and experimental UTI. METHODS Mgb-/-, Mgb+/-, and wild-type female mice underwent serial ultrasound and urine culture...

Urinary tract infection is common in children. Before the age of 6 months; boys are more susceptible to UTI than girls thereafter, the incidence is substantially higher in girls than in boys .Up to 11.3% of girls and 3.6% of boys studied in UK will have had an UTI by age 16years .UTI is usually caused by gram-negative organisms, especially Escherichia coli which accounts for about 80% of all pa...

Bacterial urinary tract infection (UTI) occurs in approximately 14% of dogs in their lifetime, with a variable age of onset. Animals with a UTI can present with stranguria, pollakiuria, dysuria and urinary incontinence, although some animals may have no clinical signs. Spayed female dogs are at increased risk for a UTI, which is likely due to anatomic differences as well as possible protective ...