نتایج جستجو برای: refractory temporal lobe epilepsy

تعداد نتایج: 377244  

Journal: :روانپزشکی و روانشناسی بالینی ایران 0
سید محمد علی قریشی زاده mohammad ali ghorayshyzadeh razy psychiatric hospital, elgholi road, tabriz, i. r. iran.تبریز، جاده ایل گلی، بیمارستان روانپزشکی رازی

psychiatric disorders are very prevalent in epilepsy, 30 to 50 percent of epileptic patients suffer from psychiatric problems. on the other hand, many psychiatric disorders such as dissociative disorder, sleep disorder, impulse control disorder and cyclic disorders have clinical features like epilepsy. therefore, differential dagnosis is very important in dealing with epilepsy. epilepsy has man...

2018
Warren W. Boling

Surgery of temporal lobe epilepsy is the best opportunity for seizure freedom in medically intractable patients. The surgical approach has evolved to recognize the paramount importance of the mesial temporal structures in the majority of patients with temporal lobe epilepsy who have a seizure origin in the mesial temporal structures. For those individuals with medically intractable mesial tempo...

2004
John W. McDonald Michael V. Johnston

We examined binding to excitatory amino acid and inhibitory amino acid receptors in frozen hippocampal sections prepared from surgical specimens resected from 8 individuals with medically refractory temporal lobe epilepsy. The excitatory receptors studied included N-methyl-D-aspartate (NMDA), strychnine-insensitive glycine, phencyclidine, and quisqualate. The inhibitory receptors studied were g...

2015
Suzanne F. C. Miller-Delaney Kenneth Bryan Sudipto Das Ross C. McKiernan Isabella M. Bray James P. Reynolds Ryder Gwinn Raymond L. Stallings David C. Henshall

Temporal lobe epilepsy is associated with large-scale, wide-ranging changes in gene expression in the hippocampus. Epigenetic changes to DNA are attractive mechanisms to explain the sustained hyperexcitability of chronic epilepsy. Here, through methylation analysis of all annotated C-phosphate-G islands and promoter regions in the human genome, we report a pilot study of the methylation profile...

Journal: :Epilepsy & behavior : E&B 2015
Ali A Asadi-Pooya Maromi Nei Ashwini Sharan Michael R Sperling

PURPOSE As the initial symptoms of epileptic seizures, many types of auras have significant localizing or lateralizing value. In this study, we hypothesized that the type of aura may predict postsurgical outcome in patients with medically refractory temporal lobe epilepsy (TLE) and mesial temporal sclerosis (MTS). METHODS In this retrospective study, all patients with a clinical diagnosis of ...

Journal: :Journal of neurology, neurosurgery, and psychiatry 2003
F Zubler M Seeck T Landis F Henry F Lazeyras

BACKGROUND Proton magnetic resonance spectroscopy (MRS) of the hippocampus is useful in lateralising the epileptic focus in temporal lobe epilepsy for subsequent surgical resection. Previous studies have reported abnormal contralateral MRS values in up to 50% of the patients. OBJECTIVE To identify the contributing factors to contralateral damage, as determined by MRS, and its extension in pat...

Journal: :Journal of neurosurgery 2012
Daipayan Guha Tim-Rasmus Kiehl Timo Krings Taufik A Valiante

Schwannomas of the brain parenchyma are extremely rare, occurring mostly in children and young adults. Fewer than 50 cases have been reported in the English-language literature. Isolated temporal lobe epilepsy is a rare presentation of intracerebral schwannomas, with only 2 reported cases. The authors present the case of a 51-year-old woman with a 4-year history of medication-refractory seizure...

2015

Patients with temporal lobe epilepsy account for about 30 to 40% of the pharmacoresistant epilepsy and can be associated with impairments in multiple cognitive domains, including memory, language, executive function, intelligence and motor speed. Research studies investigating the generalized nature of cognitive impairment in temporal lobe epilepsy, which accounts for the commonest form of foca...

2013
Silvia B. Bonelli Pamela J. Thompson Mahinda Yogarajah Robert H. W. Powell Rebecca S. Samson Andrew W. McEvoy Mark R. Symms Matthias J. Koepp John S. Duncan

Anterior temporal lobe resection controls seizures in 50-60% of patients with intractable temporal lobe epilepsy but may impair memory function, typically verbal memory following left, and visual memory following right anterior temporal lobe resection. Functional reorganization can occur within the ipsilateral and contralateral hemispheres. We investigated the reorganization of memory function ...

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