In this issue of Circulation, Bursi et al 1 report that ischemic mitral regurgitation is a more common finding after myocardial infarction (MI) than was previously thought and is an independent predictor of heart failure and death among 30-day infarct survivors. Seldom is mitral regurgitation actively investigated, and investigation is often only prompted by clinical examination. The data Bursi...

Left atrial dissection does occur, though rarely, after mitral valve surgery. A 68-year-old Korean female presented with moderate mitral stenosis, mild mitral regurgitation, moderate tricuspid regurgitation and mild aortic regurgitation. She was scheduled for mitral valve replacement and tricuspid annuloplasty. We experienced a left atrial dissection after weaning from cardiopulmonary bypass an...

Regurgitation esophagitis is a constant and intractabe complication of the conventional esophagogastrostomy. A simple valvular and fundic formation was seen to abolish the distress''. No visual regurgitation was proved on the upper G.I. series as studied in 17 cases. Using a radioisotopic method, the present study was designed to demonstrate the absence of esophageal regurgitation among those p...

Thirty four patients with aortic regurgitation were studied by continuous wave Doppler ultrasound. In 30 of these the regurgitation was graded by cineangiography as mild, moderate, or severe and in four severe regurgitation was confirmed at operation. The half times of the aortoventricular pressure differences obtained with Doppler compared well with those obtained from pressure recordings at c...

Echocardiographic mitral valve E point-septal separation (EPSS) has been found to be a useful hemodynamic index. Prior studies have shown a high negative correlation between EPSS and left ventricular ejection fraction (EF) in selected patients, but the utility of this index with valvular heart disease has not been examined in detail. Cardiac catheterization and M-mode echocardiographic data wer...

OBJECTIVE To determine the prevalence and characteristics of left sided valvar regurgitation in normal children and adolescents. DESIGN Prospective observational study. SETTING Tertiary paediatric referral centre. PATIENTS 329 volunteers (194 male, 135 female, age range 3-18 years). MAIN OUTCOME MEASURES Detection of regurgitation with colour flow mapping after valve closure. Measuremen...

BACKGROUND Aortic valve regurgitation is usually caused by impaired coaptation of the aortic valve cusps during diastole. Hypercholesterolemia produces aortic valve lipid deposition, fibrosis, and calcification in both mice and humans, which could impair coaptation of cusps. However, a link between hypercholesterolemia and aortic regurgitation has not been established in either species. The pur...

OBJECTIVES To evaluate dependence of posture and exercise on the degree of mitral regurgitation using combined first pass and equilibrium radionuclide cardiography. DESIGN 24 patients with clinically stable chronic mitral regurgitation and sinus rhythm were studied by first pass list mode and simultaneous multigated frame mode equilibrium radionuclide cardiography using red cells labelled wit...