The most common optic neuropathy is the glaucomatous neuropathy. It involves progressive loss of retinal ganglion cells including their axons and disc damage resulting in visual field loss. The disease, if not treated, can lead to irreversible vision loss. Apart from the age-related macular degeneration glaucoma is the main cause of blindness in civilized countries. Until recently the diagnosis...

BACKGROUND We evaluated the relation of systemic blood pressure with intraday variations in ocular perfusion pressure and intraocular pressure in patients with primary open-angle glaucoma in a telemedical home monitoring scenario. MATERIAL/METHODS In the project Teletonometry Mecklenburg-Vorpommern (TTMV) patients were equipped with a home monitoring system for 24-hour self-measurements of in...

Shadow-mask-assisted flattening and deposition method fabricates wearable intraocular pressure sensors on flexible hydrogel surfaces.

The objective of the study was to evaluate the antiglaucoma effect of calcium channel blockers diltiazem and verapamil. Albino rabbits were used and chronic glaucoma was induced in them using freshly prepared 150 units of alphachymotrypsin. 0.1 mL of drug solution was administered topically into the left eye whereas the right served as control. The pressure recording was carried out at 15, 30, ...

Sixty-one patients with ocular hypertension (1 17 eyes) were followed up for I to 11 years (average 40 7 months). Ten patients (12 eyes) developed visual field defects and optic disc lesions of glaucomatous type ( 10 2 %). Their average age was lower than the average of the sample, and the defect appeared between 1 and 5 years (average 41 3 months). The risk of developing glaucoma was related t...

BACKGROUND The purpose of this study was to assess the safety and efficacy of fixed-combination brinzolamide 1%/timolol 0.5% (BRINZ/TIM-FC) compared with concomitant brinzolamide 1% and timolol 0.5% (BRINZ + TIM) in Japanese patients with open-angle glaucoma (primary open-angle, exfoliation, pigmentary) or ocular hypertension. METHODS This randomized, double-masked, multicenter, parallel-grou...