Background Evaluating and controlling confounders are necessary when investigating molecular pathogenesis using human postmortem brain tissue. Particularly, tissue pH RNA integrity number (RIN) valuable indicators for confounders. However, the influences of these on expression each gene in have not been fully investigated. Therefore, we aimed to assess effects expressions samples. Methods We is...

RNA sequencing has become widely used in gene expression profiling experiments. Prior to any RNA sequencing experiment the quality of the RNA must be measured to assess whether or not it can be used for further downstream analysis. The RNA integrity number (RIN) is a scale used to measure the quality of RNA that runs from 1 (completely degraded) to 10 (intact). Ideally, samples with high RIN (>...

The technology of fluoro-deoxyglucose positron emission tomography (PET) has drastically increased our ability to visualize the metabolic process of numerous neurological diseases. The relationship between the methodological noise sources inherent to PET technology and the resulting noise in the reconstructed image is complex. In this study, we use Monte Carlo simulations to examine the effect ...

The gray scale digital image is an aggression of intensity values, represented in the form of two-dimensional array. But the digital images get corrupted by noise during acquisition and transmission. Noise is termed as any irrelevant data that obscures the authenticity of original data. Several noise removal algorithms are applied to ultrasound images in order to remove/reduce the noise level a...

We describe a Yb-fiber-based laser comb, with a focus on the relationship between the net-cavity dispersion and frequency noise on the comb. While tuning the net-cavity dispersion from anomalous to normal, we measure the relative intensity noise, offset frequency (f(CEO)) linewidth, and the resulting frequency noise spectrum on the f(CEO). We find that the laser operating at zero net-cavity dis...

Networks of neurons in the cerebral cortex operate in regime that are typically characterized by high levels of ‘noise’. Contrary to many sources of noise in physical systems, the neuronal noise is generated for the most part internally, through the highly irregular nature of neuronal discharges, in awake animals in particular. It is still highly debated how neurons and populations of neurons m...

Networks of neurons in the cerebral cortex operate in regime that are typically characterized by high levels of ‘noise’. Contrary to many sources of noise in physical systems, the neuronal noise is generated for the most part internally, through the highly irregular nature of neuronal discharges, in awake animals in particular. It is still highly debated how neurons and populations of neurons m...

noise is considered as one of the harmful factors at industrial environments. it affects human health in different aspects including harmful influences on auditory, vision, neurological and psychiatric systems, hormones, physiological and mental systems. paying attention to the importance of hormonal effects on human body seems to possess crucial importance. the aim of the present study is to i...