Acute kidney injury is a frequent complication affecting many hospitalized patients and is associated with increased morbidity and mortality. Acute kidney injury often occurs in conjunction with critical illness, which is a hypermetabolic state presenting with hyperglycemia, insulin resistance, hypertriglyceridemia, and increased protein catabolism. In addition to addressing these changes, the ...

Renal injury is a common clinical problem in the critically ill patient, and is associated with poor outcome [1,2]. Two large multicentre cohort studies reported previously the occurrence of renal injury in an estimated 30-40% of all patients admitted to the ICU [3,4]. Furthermore, critically ill patients who develop renal injury and require renal replacement therapy, have mortality rates of 50...

Background: A systematic review and meta-analysis were conducted to explore the clinical efficacy coagulation function of regional citrate anticoagulation (RCA) in continuous renal replacement therapy (CRRT) critically ill patients, provide an effective treatment options for CRRT severe patients.

BACKGROUND: COVID-19 has been at the forefront of public and scientific attention since initial report in December 2019. The kidney is one target organs the causative SARS-CoV-2 virus. OBJECTIVE: aim this article to discuss current understanding renal disease from a primary care perspective, with caveat that our knowledge pathogenesis, clinical course outcome still rapidly evolving. DISCUSSION:...

BACKGROUND Ambulatory blood pressure recordings have been shown to correlate better with target organ damage than have isolated clinic blood pressure readings. There have been some small studies demonstrating that abnormal blood pressure diurnal rhythm is common in uraemia and in patients on renal replacement therapy. Abnormal blood pressure diurnal rhythm itself may be a risk factor for accele...