This discussion of the evolution of psychiatric knowledge concerning psychogenic non-epileptic seizures (PNES) sheds light on the epistemological assumptions underlying the concept and on its practical implications as well. PNES are defined as repeated seizures or attacks which can be mistaken for epilepsy because of the similar behavioral changes displayed, but which differ in that they are no...

Sanjad-Sakati Syndrome, also referred to as Hypoparathyroidism-Retardation-Dysmorphism Syndrome or Middle East was first reported in Saudi Arabia 1988 and later a definitive report by (Sanjad et al.) 1991. It is rare autosomal recessive condition almost exclusively the Arab population. The characterized an extensive array of symptoms, including congenital hypoparathyroidism, severe growth devel...

A 23-year-old female patient treated with 900 mg oxcarbazepine for complex partial seizures is presented. Good seizure control and slight fever were noted a few weeks after drug administration. Reduction of oxcarbazepine and replacement with valproate resulted in a transient normothermia. Because of fever reappearance, vigabatrin was added and valproate was gradually reduced. Seizures reappeare...

introduction: this study was aimed to asses the rate of recurrence after the first unprovoked seizure in children. methods and materials: in a prospective study, we recruited 145 children who presented with primary unprovoked seizure and were followed for at least 12 months after the first seizure. results: seventy five children (51.7%) experienced subsequent seizures. the cumulative risk of se...

Status epilepticus (SE) in pregnancy is very rare, and there are only a few case reports of refractory SE (RSE) during pregnancy. The patient was a 27-year-old primigravida woman with a 21-year history of seizures from cortical dysplasia. At 23 weeks of pregnancy, the patient's seizure frequency progressively increased, and the patient came to the ER in a confused mental state and with intermit...

Serious complications after carbamazepine poisoning, such as coma, seizures, respiratory failure, cardiac conduction abnormalities, and death are more likely with serum levels greater than 170 micromol L(-1). We report a case of a single massive carbamazepine overdose in a 19-year-old male, following attempted suicide, without prior history of seizure disorder. On admission, three hours after i...

In typical hemolytic uremic syndrome (HUS) approximately 25% of patients show central nervous system (CNS) involvement often leading to serious long-term disabilities. We used the C5-complement inhibitor Eculizumab as rescue therapy. From 2011 to 2014, 11 children (median age 22 months, range 11-175) with enterohemorrhagic Escherichia coli-positive HUS requiring dialysis who had seizures (11/11...

OBJECTIVE To evaluate serum phenobarbitone levels in neonates with seizures and to evaluate the effect of repeated loading dose on serum phenobarbitone levels. METHODS In this prospective observational study conducted in a tertiary care centre of Northern India during 2011- 2012, 99 neonates admitted with seizureswere included.Serum phenobarbitone levels in neonates with seizures at 20 minute...