نتایج جستجو برای: respiratory syncytial virus
تعداد نتایج: 581270 فیلتر نتایج به سال:
AIM To increase awareness of possible pitfalls in the design and analysis of a multi-centre randomized clinical trial and to give an overview of alternative study designs and their consequences for power analyses in case of limited availability of trial participants. METHODS Investigation of the assumptions in the power calculation and re-analysis of the original data of a 'failed' trial on t...
1Ibaraki Prefectural Institute of Public Health, Ibaraki 310-0852; 2Gunma Prefectural Institute of Public Health and Environmental Sciences, Gunma 371-0052; 3Ibaraki Joso Health Center, Ibaraki 303-0005; 4Infectious Disease Surveillance Center, 5Department of Virology III, and 7Pathogen Genomics Center, National Institute of Infectious Diseases, Tokyo 208-0011; and 6Department of Molecular Biod...
1999;155:841–51. 24. Beyer M, Bartz H, Horner K, et al. Sustained increases in numbers of pulmonary dendritic cells after respiratory syncytial virus infection. J Allergy Clin Immunol 2004;113:127–33. 25. Brimnes MK, Bonifaz L, Steinman RM, et al. Influenza virus-induced dendritic cell maturation is associated with the induction of strong T cell immunity to a coadministered, normally nonimmunog...
Neutrophils induce damage to respiratory epithelial cells infected with respiratory syncytial virus.
The mechanisms by which respiratory syncytial virus (RSV) infection induces bronchiolitis and airway disease are unclear. The presence of large numbers of polymorphonuclear leukocytes (PMN) in the airways of infants with RSV infection suggests a potential role of PMN in airway injury associated with RSV infection. To investigate the potential role of neutrophils in RSV bronchiolitis, human alve...
Radiolabeled respiratory syncytial virus was purified from medium that had been harvested from infected HeLa cell monolayers before it contained much cellular debris. After isopycnic centrifugation in linear gradients prepared with sucrose dissolved in Hanks balanced salt solution, almost all the infectivity and most of the radioactivity were recovered in a single band with density from 1.16 to...
Antibody-mediated clearance of respiratory syncytial virus from cotton rat pulmonary tissues occurs in the absence of complement and in the absence of the Fc portion of the immunoglobulin G molecule, suggesting that complement-independent, cell-independent neutralization is the major mechanism of clearance.
IMPORTANCE Infection with the respiratory syncytial virus (RSV) is the leading cause of hospitalizations in children, accounting for more than 90,000 hospitalizations every year in the United States. For children who are at risk for severe RSV infections, the American Academy of Pediatrics recommends immunoprophylaxis with a series of up to 5 injections of the antibody palivizumab administered ...
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