objective(s) in this study, a kind of ph sensitive composite membrane was prepared and drug permeation through it was investigated in terms of ph. rationale of this study originated from the fact that a ph change which may be a result of a disease state in the body can trigger drug release. materials and methods  here, a kind of ph sensitive composite membrane containing different nanoparticle ...

Redox-active stimuli have gained a great deal of interest as an indicating factor for designing bioresponsive matrices in gene delivery. Hence, a wide range of gene carriers has been designed incorporating the redox-stimuli characteristics. The most important type of gene carriers is the class of redox responsive polymers. Among them, disulfide incorporated redox-responsive polyethyleneimine (P...

Introduction: Stimuli-responsive hydrogels, which indicate a significant response to the environmental change (e.g., pH, temperature, light, …), have potential applications for tissue engineering, drug delivery systems, cell therapy, artificial muscles, biosensors, etc. Among the temperature-responsive materials, poly (N-isopropylacrylamide) (PNIPAAm) based hydrogels have been widely developed ...

The common marmoset (Callithrix jacchus) is one of the smallest species of primates, with high visual recognition abilities that allow them to judge the identity and quality of food and objects in their environment. To address the cortical processing of visual information related to material surface features in marmosets, we presented a set of stimuli that have identical three-dimensional shape...

Cholesteric liquid crystals (CLCs) are a major class of photonic materials that display selective reflection properties arising from their helical ordering. The temperature response CLCs, comprising dynamic color changes upon variation temperature, is exploited using material systems consisting small mesogenic molecules, polymer-dispersed (PDLCs), polymer-stabilized (PSLCs), or liquid-crystalli...

dopa responsive dystonia (drd) is a dystonic syndrome of childhood, usually affecting gait and subsequently developing into parkinsonism with a dramatic therapeutic response to levodopa. at the best of our recollection this is the first case in iranian medical literature of a 13 year old boy, affected by this interesting, rare and treatable disease which can be easily diagnosed if clinicians ha...

admiration for environment in general needs to be profoundly rooted in an understanding of history. urban history is unique not only in the fact that it reflects climate but also in that it cuts across many different fields. in most schools of urban studies many aspects of science and technology are taught with relation to design in order to attain skills for practice. during a student’s later ...

The distinction between material behavior (mechanics) and material response (electronics) in the framework of responsive building skins has promoted unique design protocols for integrating sensor technologies into material components. Such a distinction results in the implementation of remote sensing devices post the process of material fabrication. Sensors are commonly perceived as electronic ...

Background: Dopa responsive dystonia (DRD) is a disorder characterised by childhood onset dystonia but a wide range of clinical presentations has now been described. Objective: To study a large Canadian family with presumed DRD. Methods: The clinical features of the family were collected before molecular genetic mutational analysis. Results: All nine individuals in whom a clinical diagnosis of ...