BACKGROUND Heart transplant is a treatment option for selected patients with hypertrophic cardiomyopathy (HCM). However, the prevalence, clinical profile, and outcome of this subgroup of HCM patients are uncertain. Therefore, we sought to determine the occurrence, clinical characteristics, and prognosis of HCM patients who underwent cardiac transplantation in the United States during a 15-year ...

Cardiomyopathies are a group of diseases characterized by the structural and functional abnormalities heart muscles in absence other illnesses that might be responsible for observed myocardial anomaly. Hypertrophic dilated cardiomyopathies most prevalent types. Rare types include restrictive cardiomyopathy with arrhythmia. Dilated has documented prevalence 36 cases per 100,000 population Europe...

A 52-year-old woman with rheumatoid arthritis who had been treated with prednisone and hydroxychloroquine for >12 years presented with chest discomfort and a seizure. She was diagnosed with restrictive cardiomyopathy combined with sick sinus syndrome. A myocardial muscle biopsy was performed to identify the underlying cardiomyopathy, which showed marked muscle fiber hypertrophy, fiber dropout, ...

BACKGROUND In recent years, non-syndromic idiopathic cardiomyopathies have increasingly been characterised as autosomal dominant conditions caused by single gene mutations. Loci have been identified for hypertrophic and dilated cardiomyopathy, and in some cases the same loci are associated with restrictive cardiomyopathy (RCM). In a kindred with RCM that we previously reported, we ruled out the...

Cardiovascular diseases are common in cats. 3 Myocardial disorders are the major cause of heart failure and thromboembolism, with idiopathic hypertrophic cardiomyopathy the most important of the primary myocardial diseases. Extensive myocardial fibrosis leading to a restrictive cardiomyopathy or right ventricular cardiomyopathy is now recognized on a regular basis in mature cats. Conversely, di...

Primary heart muscle disease is a cause of significant morbidity and mortality in childhood. The current WHO classification of cardiomyopathy is based on a combination of clinical features, aetiology and pathology. It is in need of revision because of accumulating genetic information concerning the pathogenesis of cardiomyopathy. It is becoming increasingly obvious that most of the primary hear...

Diabetes mellitus-related cardiomyopathy (DMCMP) was originally described as a dilated phenotype with eccentric left ventricular (LV) remodelling and systolic LV dysfunction. Recently however, clinical studies on DMCMP mainly describe a restrictive phenotype with concentric LV remodelling and diastolic LV dysfunction. Both phenotypes are not successive stages of DMCMP but evolve independently t...

By definition, myocardiopathies or cardiomyopathies (CM) are heart muscle diseases that cause structural and functional myocardial abnormalities in the absence of coronary artery disease, hypertension, valvular congenital disease., CM constitute a very heterogeneous group one leading causes death either from end-stage failure sudden due to arrythmias. According phenotype, may be classified into...