PURPOSE To investigate the relationship between retinal nerve fiber layer (RNFL) thickness and peripheral grating resolution acuity (PGRA) as well as differential light sensitivity (DLS) in healthy subjects and patients with early glaucoma. The agreement between estimates of retinal ganglion cell (GC) density from each functional test is explored. METHODS PGRA was measured in 24 patients with...

PURPOSE To determine the diagnostic ability of retinal vessel diameter (RVD) measurements and the factors related to retinal vascular diameters in patients with open-angle glaucoma (OAG). METHODS This retrospective observational study included 145 patients with OAG (63 with high-tension and 82 with low-tension glaucoma) and 60 healthy controls. The central retinal arteriolar equivalent (CRAE)...

Introduction: Non-arteritic ischemic optic neuropathy (NAION) is the second most common in adults. Since circulatory insufficiency presumed to have a role pathogenesis of NAION, optical coherence tomography angiography (OCTA) suggested as tool assessing NAION patients, while (OCT) can detect structural changes. This case report aims describe congruity visual field defect with OCT and OCTA resul...

BACKGROUND In clinical practice, the differentiation of glaucomatous from non-glaucomatous cupping can be difficult, even for experienced observers. The purpose of this study was to evaluate the role of optical coherence tomography (OCT) in differentiating glaucomatous from non-glaucomatous optic nerve cupping in a cross-sectional pilot study. METHODS Eleven consecutive patients presenting to...

Abstract Background To assess the diagnostic capability of novel Bruch’s membrane opening (BMO)-based disc parameters, BMO-minimum rim width (BMO-MRW) and area (BMO-MRA) in Chinese population compare them to retinal nerve fiber layer (RNFL) from optical coherence tomography (OCT) (RA) Heidelberg tomograph-III (HRT-III). Methods In total, 200 eyes 77 healthy 123 primary open-angle glaucoma (POAG...

PURPOSE To describe and test a method for assessment of the monkey retinal nerve fiber layer (RNFL) with scanning laser polarimetry. METHODS A scanning laser polarimeter was modified to accommodate a variable corneal polarization compensator. Corneal polarization magnitude (CPM) and corneal polarization axis (CPA) of the anterior segment birefringence of normal and glaucomatous cynomolgus mon...

BACKGROUND/AIMS To investigate the patterns of retinal ganglion cell damage at different stages of glaucoma, using the circumpapillary retinal nerve fiber layer (RNFL) and macula ganglion cell-inner plexiform layer (GCIPL) thicknesses. METHODS In 296 eyes of 296 glaucoma patients and 55 eyes of 55 healthy controls, the correlations of mean deviation (MD) with the superior and inferior quadran...

PURPOSE To demonstrate that video-rate spectral domain optical coherence tomography (SDOCT) can qualitatively and quantitatively evaluate optic nerve head (ONH) and retinal nerve fiber layer (RNFL) glaucomatous structural changes. To correlate quantitative SDOCT parameters with disc photography and visual fields. METHODS SDOCT images from 4 glaucoma eyes (4 patients) with varying stages of op...

SIGNIFICANCE This study resulted in the identification of an optic nerve head (ONH) feature associated with tilted optic discs, which might potentially contribute to ONH pathologies. Knowledge of such findings will enhance clinical insights and drive future opportunities to understand disease processes related to tilted optic discs. PURPOSE The aim of this study was to identify novel retinal ...