A tuning method with reinforcement learning (RL) for the Retina Encoder (RE) of a Retina Implant (RI) as a visual prosthesis for blind subjects with retinal degenerations is proposed. RE simulates retinal information processing in real time by means of spatio-temporal receptive eld (RF) lters and generates electrical signals for stimulation of several hundreds of ganglion cells (GC) to regain a...

To test tuning methods for the Retina Encoder RE of a Retina Implant RI as a visual prosthesis for blind subjects with retinal degenerations a suitable simulation of the patient s evaluative response to RE state al terations must be provided RE simulates real time retinal information processing and consists of several hundreds of spatio temporal receptive eld RF lters to generate electrical sig...

To evaluate the biocompatibility of subretinal implanted parylene-based Ti/Pt microelectrode arrays (MEA). Eyes were enucleated 3 months after MEAs were implanted into the subretinal space of rabbits. Morphological changes of the retinas were investigated by H&E staining. Immunohistochemical staining for glial fibrillary acidic protein and opsin were performed to evaluate changes in Muller cell...

Vision represents one of the main senses for humans to interact with their environment. Our sight relies on the presence of fully functional light sensitive cells - rod and cone photoreceptors - allowing us to see under dim (rods) and bright (cones) light conditions. Photoreceptor degeneration is one of the major causes for vision impairment in industrialized countries and it is highly predomin...