A thirteen years old male patient of i was referred to our Dermatology D knees and hands. Patient was blind since birth and diagnosis of “retinitis pigmentosa” Ophthalmology Department. He was investigated and found raised levels of blood sugar, triglycerides, VLDL, TSH, SGOT/PT and kidney functions tests. He was diagnosed as a case of eruptive xanthomas with retinitis pigmentosa in secondary h...

Retinitis pigmentosa affects 50,000-100,000 people in the United States and about 1.5 million people worldwide. Patients usually report impaired adaptation, night blindness, and loss of mid-peripheral visual field in adolescence. As the condition progresses, they lose far-peripheral visual field and eventually lose central vision as well. Some patients have become blind as early as age 30. The ...

A patient presented with unilateral findings of night blindness shown by impaired rod function and dark adaptation, constricted visual fields with good central acuity, a barely recordable electro-retinographic b-wave, and a unilaterally impaired electro-oculogram. There were none of the pigmentary changes usually associated with retinitis pigmentosa. The unaffected right eye was normal in all r...

Stiles-Crawford functions were obtained from the maculas of 22 patients with different genetic types of retinitis pigmentosa and visual acuity of 20/40 or better. Reduced cone directional sensitivity was seen in the fovea with both focal cone electroretinographic testing and psychophysical testing. Functions from the parafovea determined with psychophysical testing showed either significant fla...

A 48-year-old male patient with diabetes mellitus and retinitis pigmentosa was admitted with complaints of weakness of both lower limbs and urinary incontinence of 1year duration. Fundoscopy was suggestive of retinitis pigmentosa. On admission, the power in the legs was about Grade 2. Plain X-ray showed a sickle-shaped defect of the sacrum scimitar sacrum (Figure 1). MRI showed an anterior pres...

A loop-mediated isothermal amplification (LAMP) assay for the rapid detection of cytomegalovirus (CMV) was developed and evaluated. The LAMP assay specifically amplified only CMV DNA, and no cross-reactivity with the DNA of herpes simplex virus type 1, varicella-zoster virus, adenovirus, Aspergillus flavus, or Staphylococcus aureus was observed. The sequences of the LAMP assay-positive CMV prod...

Oral valganciclovir is a new and highly efficacious alternative to the chronic administration of ganciclovir in the treatment of cytomegalovirus (CMV) retinitis in HIV-infected patients. In addition to its excellent bioavailability and favorable pharmacokinetic profile, valganciclovir has also proved cost effective and is the most widely used drug in the armamentarium for the treatment of CMV r...

BACKGROUND Acute retinal necrosis is a rare but devastating ocular condition. We report two cases of acute retinal necrosis in immunocompetent patients, complicated by cystoid macular oedema and treated with intravitreal dexamethasone (OZURDEX®) implant. RESULTS Two patients diagnosed with acute retinal necrosis were treated with intravenous acyclovir. Both of them developed cystoid macular o...

PURPOSE To describe the treatment of cytomegalovirus (CMV) retinitis with intravitreal sustain-release ganciclovir devices in a 16-year-old patient in third remission of acute lymphoblastic leukemia after stem cell transplantation. METHODS The patient received a stem cell transplant from an unrelated bone marrow donor after which he contracted a serious CMV infection manifested in the lungs a...