The effect of adrenalectomy on 7,12-dimethyl benz(a)anthracene-induced mammary tumor growth was studied in Sprague-Dawley female rats. Weekly measure ments revealed that adrenalectomy significantly increased both mammary tumor size and number and elevated serum prolactin levels as compared to the intact controls. Daily injection of 1 mg hydrocortisone acetate into the intact 7,12dimethylbenz(a)...

background: cushing's disease is the most prevalent cause of endogenous adrenocorticotrophic hormone hypersecretion. the aim of this study was to document the current clinical practice pattern in the management of cushing's disease by iranian endocrinologists to determine their opinions and compare them with the current clinical practice guidelines.    methods: an eight-item questionn...

BACKGROUND Inflammatory pseudotumors were mostly encountered in the lung. Retroperitoneal inflammatory pseudotumors are relatively rare. Although laparoscopic surgery with a modified flank position is widely performed for retroperitoneal tumors, we placed the patient in the supine position to maintain the normal anatomical view of the retroperitoneal space. We report a case of retroperitoneal i...

We aimed to compare the safety and patient outcomes of retroperitoneal paraganglioma (PG) following the retroperitoneoscopic and transperitoneoscopic approaches based on large samples.Seventy-four patients with retroperitoneal PG undergoing laparoscopic resection from June 2004 to September 2013 were retrospectively included. The patients were divided into the retroperitoneal (n = 40) and trans...

The relative rates of protein (hormone) synthesis and secretion by the various cell types in the anterior hypophysis of the rat have been studied by means of autoradiography. Normal and adrenalectomized male rats were injected with tritiated glycine and their hypophyses removed and fixed at 20, 40, and 90 minutes and 15 hours after injection. Autoradiograms of the hypophysial sections were prep...

BACKGROUND AND OBJECTIVES Several studies have been reported on the problem of determining when laparoscopic adrenalectomy is indicated for solitary adrenal metastasis of malignant tumors. Our efforts at answering this question constitute the basis of this report. METHODS From June 2010 to June 2011, laparoscopic adrenalectomy was performed in 10 lung cancer patients with solitary adrenal met...

The liver arginase in the rat decreases following adrenalectomy (Fraenkel-Conrat, Simpson & Evans, 1943; Folley & Greenbaum, 1946; Kochakian & Vail, 1947), and in lactating rats the mammarygland arginase behaves similarly (Folley & Greenbaum, 1946). It is possible that the decline in lactation causedby adrenalectomy (see, e.g., Cowie& Folley, 1947 a) is connected with the decrease in mammary-gl...

The aim of the present study was to present the treatment observations of patients with adrenocorticotrophic hormone (ACTH)-independent macronodular adrenal hyperplasia (AIMAH) from a single medical center. A total of 23 patients with AIMAH were retrospectively reviewed according to the clinical features of the patient. Physical symptoms and biochemical evidence of Cushing's syndrome (CS) were ...