METHADONE 17 Introduction 17 Pharmacology of methadone 17 Chemical characteristics 17 Pharmacodynamics 17 Pharmacokinetics 18 Drug interactions 19 References 22 Efficacy of Methadone in Clinical Studies 24 Figure 1. Consort – like report of Eligible Papers. 25 Summary of data for Efficacy (Table 1, Appendix 1). 26 Search Method 26 Systematic Review (Table 3, Appendix 1). 28 Retrospective Studie...

OBJECTIVE To examine the sexual behaviour and the prevalence of sexually transmitted diseases among adolescent girls who attended the Genito-Urinary Medicine Clinic in Birmingham. DESIGN Retrospective case control study. SETTING The Genito-Urinary Medicine Clinic (Ward 19), General Hospital, Birmingham. SUBJECTS 159 adolescent girls aged 13-16 years; 215 female clinic attenders older than...

PURPOSE The National Health Insurance Service-National Sample Cohort and medical checkup data from 2002 to 2013 were used to evaluate the association between periodontal surgery for the treatment of periodontitis (PSTP) and vasculogenic erectile dysfunction (VED). METHODS Bivariate and multivariate logistic regression analyses were applied to a longitudinal retrospective database to assess th...

conclusions: the potent effect of corticosteroids in the rapid improvement of respiratory compromise associated with thyroid lymphoma represents an important clinical finding. this opens the possibility for the favorable response to corticosteroid therapy to be regarded as a possible preliminary diagnostic tool for thyroid lymphoma in acute respiratory distress patients in the absence of trache...

Early-onset cataracts are associated with insufficient antioxidative activity, and, therefore, a potential risk of cancer. This study investigated the risk of cancer after being diagnosed with early-onset cataracts. Retrospective claims data from the Taiwan National Health Insurance Research Database were analyzed. Study subjects were comprised of patients with early-onset cataracts, aged 20-55...

BACKGROUND This study was designed to determine the role of primary repair and to investigate the possibility of expanding indications for primary repair of colon injuries using nonselective approach. METHODS Two groups of patients were analyzed. Retrospective (RS) group included 30 patients managed by primary repair or two stage surgical procedure according to criteria published by Stone (S/...

purpose: to examine and compare the prevalence of different types of mental disorders among the administrative staff and warders of the central prison of sistan and baluchestan. materials and methods: the study population included all employees of zahedan general office of prisons. the sample consisted of 100 employees, of whom fifty individuals worked in various administrative units of zahedan...