نتایج جستجو برای: rflps

تعداد نتایج: 641  

Journal: :Annals of human genetics 2002
A Brehm L Pereira H-J Bandelt M J Prata A Amorim

In order to study the matrilineal genetic composition in Cabo Verde (Republic of Cape Verde), an archipelago that used to serve as a Portuguese entrepôt of the Atlantic slave trade, we have analysed a total of 292 mtDNAs sampled from the seven inhabited islands for the hypervariable segment I (HVS-I) and some characteristic RFLPs of the coding regions. The different settlement history of the no...

Journal: :Journal of medical genetics 1983
K E Davies J Jackson R Williamson P S Harper S Ball M Sarfarazi L Meredith G Fey

Variations in DNA sequence generate polymorphisms which can be followed through families. A cloned gene specific probe for human complement 3 (C3) was hybridised to DNA samples digested with restriction endonucleases. The C3 probe detects several restriction fragment length polymorphisms (RFLPs) that occur frequently in the general population. These DNA alleles can be readily used in linkage an...

Journal: :Nucleic acids research 1990
J G Williams A R Kubelik K J Livak J A Rafalski S V Tingey

Molecular genetic maps are commonly constructed by analyzing the segregation of restriction fragment length polymorphisms (RFLPs) among the progeny of a sexual cross. Here we describe a new DNA polymorphism assay based on the amplification of random DNA segments with single primers of arbitrary nucleotide sequence. These polymorphisms, simply detected as DNA segments which amplify from one pare...

Journal: :Psychological medicine 1988
M J Owen S A Whatley

The remarkable recent advances in molecular genetics are grounds for considerable optimism in psychiatry, where many diseases appear to have an hereditary component. Most notably, the discovery of restriction fragment-length polymorphisms (RFLPs) has greatly increased the number of markers available for linkage studies. Linkage analysis has two basic requirements. First, co-operative families m...

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