Postpartum injections of 250 ,tg of anti-D gammaglobulin prevent Rh-immunization of Rh-negative women, with an im-munosuppression success rate of approximately 95% (Eklund and Nevanlinna, 1971). The average fetomaternal transfusion, however, is less than 1-5 ml in 98% of cases (Clarke et al., 1966), and so far there are few observations on trying to suppress primary Rh-immunization due to massi...

It has been shown that the frequency of ABO blood groups differs between populations [1,3]. Determination of the frequency of blood groups in a particular region facilitates timely provision of blood and blood products. There are many studies on the distribution of blood groups in Turkey [4-10]; however, none have considered Kayseri Province, a densely populated city in central Anatolia. As suc...

Background: RhD antigen system is the leading cause of hemolytic disease of the fetus and newborn (HDFN). Paternal molecular RhD zygosity test is valuable to decide on the use of anti-D immunoglobulin prophylaxis in Rh D-negative pregnant women. We aimed to investigate the paternal RhD zygosity by two molecular methods among blood donors in Kurdistan province, the west of Iran. We also compared...

BACKGROUND Screening of blood is mandatory for transfusion transmitted diseases and is routinely done in the blood banks. As blood is the major source transmission of hepatitis B, hepatitis C, human immunodeficiency virus & many other diseases the hazards can be minimised by effective donor selection and screening. AIM To find out the correlation between the transfusion transmitted diseases a...

African individuals harbor molecular RH variants, which permit alloantibody formation to high-prevalence Rh antigens after transfusions. Genotyping identifies such RH variants, which are often missed by serologic blood group typing. Comprehensive molecular blood group analysis using 3 genotyping platforms, nucleotide sequencing, and serologic evaluation was performed on a 7-year-old African mal...

Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder in human. The aim of this study was to determine the prevalence of G6PD deficiency among children and evaluate its association with ABO/Rh blood groups. Method: Blood samples of 3401 asymptomatic children were analyzed and compared with 317 children who were admitted to hospital because of hemolys...

Background & Aims: Cutaneous leishmaniasis (CL) is a health problem, especially in tropical and subtropical countries. In spite of new scientific developments in recent years, several questions related to this disease have been raised that have still no answer. The objective of this research was to study the epidemiology of CL and its relationship with blood groups in the city of Bam in 2007...

The use of transfusion therapy for sickle cell disease (SCD) is increasing due to expanded indications, increased availability of erythrocytapheresis, and oral chelators to treat transfusional iron overload. However, alloimmunization to red blood cell (RBC) blood group antigens remains a major complication for patients with SCD and often presents significant challenges in their medical manageme...