Background: Corrosive esophageal burns have high morbidity and mortality. The effective treatment is controversial. In our study, we aimed to examine the effects of resveratrol (RSV) platelet rich plasma (PRP) on healing in corrosive esophagitis model rats. 
 Material methods: A total 24 rats were randomly divided into 4 groups each as esophagitis, control, PRP RSV groups. No was administe...

Myocardial infarction is the leading cause of death in world’s population. The sudden and progressive loss cardiomyocyte contractile cells due to disproportionate number new formation. This pathological condition will ultimately reduce function heart muscles. Platelet-rich plasma (PRP) last decade has been attracting attention regarding its role cell regeneration. content cytokines growth facto...

BACKGROUND Concentrated leukocytes in leukocyte- and platelet-rich plasma (L-PRP) may deliver increased levels of pro-inflammatory cytokines to activate the NF-κB signaling pathway, to counter the beneficial effects of growth factors on osteoarthritic cartilage. However, to date no relevant studies have substantiated that in vivo. MATERIAL AND METHODS Autologous L-PRP and pure platelet-rich pla...

Objective: The objective of this study was to assess average improvement in maximal mouth opening, pain at rest, and active opening after platelet-rich plasma (PRP) injections using ultrasonography (USG)-guided platelets rich injection the management internal derangement joint. Materials Methods: Ten patients with temporomandibular joint (TMJ) underwent PRP guided by ultrasonography. extent pai...

  Background: Osteoarthritis is a disabling musculoskeletal disease with no definite treatment. This study compared the effect of Platelet-rich plasma (PRP) and Transcutaneous Electrical Nerve Stimulation (TENS) plus exercise in the treatment of patients with knee joint osteoarthritis.   Methods : 54 eligible patients with knee osteoarthritis were randomly allocated into two groups. (IRCT201211...

Abstract Background Wound healing is impaired in patients with diabetes due to the multifactorial etiology of disease, which limits therapeutic efficacy various approaches. This study hypothesizes that combination adipose-derived stem cells (ADSCs) and platelet-rich plasma (PRP) might achieve optimally efficient diabetic wound healing. Methods ADSCs were isolated from adipose tissues Sprague-Da...

BACKGROUND It is still not clear whether native or platelet count adjusted platelet rich plasma (PRP) should be used for platelet aggregation measurements. AIM To evaluate the necessity of using adjusted PRP in platelet function testing. METHODS Platelet aggregation with native PRP and adjusted PRP (platelet count: 250/nl, obtained by diluting native PRP with platelet poor plasma) was perfo...