Polyurethanes (PUs) are an exceedingly heterogeneous group of plastic polymers, widely used in a variety industries from construction to medical implants. In the past decades, we have witnessed accumulation PU waste and its detrimental environmental impacts. PUs been identified as one most toxic polymers leaching hazardous compounds derived both polymer itself additives production. Further impa...

Introduction Poly(urethane urea) multiblock copolymers [PUU] are used in variety of biomedical applications, including as blood-contacting components in ventricular assist systems. One of the drawbacks of these materials (particularly when used in completely implantable devices) is their relatively high permeability to air and moisture. Conventional biomedical PUU elastomers are generally compo...

Achieving multiple physical properties from a single material through three-dimensional (3D) printing is important for manufacturing applications. In addition, industrial-level durability and reliability necessary realizing individualized of devices using 3D printers. We investigated the architected materials composed ultraviolet (UV)-cured urethane elastomers use as insoles. The microlattice m...

OBJECTIVES A safe and effective topical prevention strategy will likely require sustained delivery of potent antiviral drugs and a delivery system that simultaneously maximizes drug distribution and overcomes the behavioural challenges related to adherence. Activity against HIV and herpes simplex virus (HSV) would be advantageous, given the epidemiological link between the two pathogens. We hyp...

The response of back-supported buffer plates comprising a solid face sheet and foam core backing impacted by a column of high velocity particles (sand slug) is investigated via a lumped parameter model and coupled discrete/continuum simulations. The buffer plate is either resting on (unattached) or attached to a rigid stationary foundation. The lumped parameter model is used to construct maps o...

Urethane ([carbonyl-(14)C]ethyl carbamate) is a fermentation by-product in alcoholic beverages and foods and is classified as reasonably anticipated to be a human carcinogen. Early studies indicated that while CYP2E1 is involved, esterases are the primary enzymes responsible for urethane metabolism. Using CYP2E1-null (KO) mice, current studies were undertaken to elucidate CYP2E1's contribution ...

OBJECTIVE The purpose of the present study was to compare inter-fragmentary compression pressures after fixation of a simulated type II odontoid fracture with the headless compression Herbert screw and a half threaded cannulated lag screw. METHODS We compared inter-fragmentary compression pressures between 40- and 45-mm long 4.5-mm Herbert screws (n=8 and n=9, respectively) and 40- and 45-mm ...

STUDY DESIGN An idealized biomechanical model. OBJECTIVE The aim of this study was to evaluate the biomechanical properties of a construct designed to minimize intervertebral cage subsidence and maximize stiffness. SUMMARY OF BACKGROUND DATA Reconstruction after vertebral resection typically involves posterior segmental fixation and anterior interbody support. However, poor bone density, ad...