PURPOSE The manifestation of Parkinson's disease (PD) is characterized by bradykinesia, resting tremor, and rigidity. The etiology of PD remains unknown. Recently several studies suggest that some environmental and genetic factors may be related to the cause of PD. Genetic variation in xenobiotic metabolizing enzymes involved in the disposition of pesticides, such as paraoxonase I (PON 1), may ...

Background and Objectives: Poisoning is an important cause of childhood and adolescence hospital emergency presentations and admissions and a major health problem in this population sector. The present study was designed to describe the epidemiology and pattern of poisoning in addition to its case fatality rate. Methods: A total of 1450 pediatric cases with poisoning admitted to the Central Tea...

OBJECTIVES The aim of the present project was to assess population exposure to pesticides in the vicinity of pesticide dump sites and make a preliminary evaluation of the potential health hazards to humans. MATERIALS AND METHODS Of the 286 pesticide dump sites registered in Poland, 40 were selected as the largest source of ecological hazard. The application of the Hazard Ranking System made i...

To combat an increasing abundance of sucking insect pests, >40 pesticides are currently recommended and frequently used as foliar sprays on row crops, especially cotton. Foraging honey bees may be killed when they are directly exposed to foliar sprays, or they may take contaminated pollen back to hives that maybe toxic to other adult bees and larvae. To assess acute toxicity against the honey b...

Organophosphate (OP) pesticides are widely used for crop protection in many countries including Thailand. Aside from causing environmental contamination, they affect human health especially by over-stimulating of the neurotransmission system. OP pesticides, as with other non-persistent pesticides, degrade quickly in the environment as well as are metabolized quite rapidly in humans. Assessing h...

Six million children live in poverty in America's inner cities. These children are at high risk of exposure to pesticides that are used extensively in urban schools, homes, and day-care centers for control of roaches, rats, and other vermin. The organophosphate insecticide chlorpyrifos and certain pyrethroids are the registered pesticides most heavily applied in cities. Illegal street pesticide...

Enchytraeidae (Oligochaeta, Annelida) are often considered to be typical forestliving organisms, but they are regularly found in agroecosystems of the temperate regions of the world. Although less known than their larger relatives, the earthworms, these saprophagous organisms play similar roles in agricultural soils (but at a smaller scale), e.g., influencing soil structure and organic matter d...

BACKGROUND Farming has been associated with rheumatoid arthritis (RA), but the role of pesticides is not known. OBJECTIVES We examined associations between RA and pesticides or other agricultural exposures among female spouses of licensed pesticide applicators in the Agricultural Health Study. METHODS Women were enrolled between 1993 and 1997 and followed through 2010. Cases (n = 275 total,...

BACKGROUND Non-Hodgkin lymphoma (NHL) is a solid tumour of lymphocytes, important elements in the immune system. According to 2006 data, in Turkey the incidence was 6.5 per 100,000 in males, and 4.4 in females. The relationship between the use of pesticides and development of NHL has been extensively investigated in many studies, and it has been demonstrated that the risk of NHL is increased by...

BACKGROUND Previous epidemiologic studies have suggested that exposure to pesticides in utero and during early childhood may increase the risk for development of childhood cancer, including Wilms tumor, a childhood kidney tumor. OBJECTIVES In this analysis we evaluated the role of residential pesticide exposure in relation to the risk of Wilms tumor in children using data from a North America...