Receiver operating characteristic (ROC) curves have application in analysis of the performance of diagnostic indicators used in the assessment of disease risk in clinical and veterinary medicine and in crop protection. For a binary indicator, an ROC curve summarizes the two distributions of risk scores obtained by retrospectively categorizing subjects as cases or controls using a gold standard....

In this paper, we propose an adaptive algorithm for bipartite ranking and prove its statistical performance in a stronger sense than the AUC criterion. Our procedure builds on the RankOver algorithm proposed in (Clémençon & Vayatis, 2008a). The algorithm outputs a piecewise constant scoring rule which is obtained by overlaying a finite collection of classifiers. Here, each of these classifiers ...

PURPOSE Basophil activation occurs both in patients with immediate hypersensitivity reactions to anti-inflammatory drugs and in healthy controls in a dose-dependent manner. Our aims were to define the optimal basophil activation test (BAT) concentration and the threshold for BAT positivity for dipyrone. METHODS From 45 patients with a positive history of an immediate hypersensitivity reaction...

Rationale and Objective. To compare logistic regression and artificial neural network for computer-aided diagnosis on breast sonograms. Materials and Methods. Ultrasound images of 24 malignant and 30 benign masses were analyzed quantitatively for margin sharpness, margin echogenicity, and angular variation in margin. These features and age of patients were used with two pattern classifiers, log...

The t-test is as defined in the previous lecture. It has slope 1/σ. The Mann-Whitney test rejects if 1 nm ∑ i,j I(Xi ≤ Yj) is large. Note. The Mann-Whitney statistic has a relationship with the area under the ROC curve (AUC) for classification algorithms with a tunable parameter. The ROC plot has one axis for proportion of false positives and one axis for proportion of true positives; as we mov...