CLINICAL SIGNIFICANCE The apical extrusion of infected debris may have the potential to disrupt the balance between microbial aggression and host defense, resulting in incidents of acute inflammation. During preparation, irrigants and debris, such as bacteria, dentin filings and necrotic tissue may be extruded into the periradicular region leading to periapical inflammation and postoperative fl...

The purpose of this study was to compare the reaction of rat subcutaneous connective tissue to 0.9% sterile saline, 2.5% sodium hypochlorite (NaOCl), 5.25% NaOCl and 2% chlorhexidine gluconate solution or gel. Six circles were demarcated on the dorsal skin of 24 male Wistar rats, leaving 2 cm between each circle. Using a syringe, 0.1 mL of each root canal irrigant was injected subcutaneously in...

INTRODUCTION The aim of the present in vitro study was to evaluate the disinfection ability of 980-nm diode laser in comparison with sodium hypochlorite (NaOCl) as a common root canal irrigant in canals infected with Enterococcus faecalis (E. faecalis). METHODS AND MATERIALS The root canals of 18 extracted single-rooted premolars were prepared by rotary system. After decoronation, the roots w...

AIM: This study assessed the effectiveness of 5 different irrigant activation systems on canal cleanliness and removal smear layer from root canals. METHODS: A total 110 mandibular premolars with straight were assigned to five groups (n = 20): conventional needle irrigation, passive ultrasonic activation, sonic EndoActivator, negative apical pressure EndoVac (EV), or EDDY system, besides a cont...

INTRODUCTION The aim of this study was to compare the antibacterial effect of Persian green tea extract (GTE) and 2.5% sodium hypochlorite (NaOCl) against Enterococcus faecalis (E. faecalis) as an intracanal irrigant. METHODS AND MATERIALS Thirty freshly extracted teeth were instrumented and sectioned into mesial and distal segments. The specimens were put into wells containing 2 mL of E. fae...

Large periapical lesions, regardless of whether they are granulomas, abscesses or cysts, are primarily caused by root canal infection. Thus the treatment protocol should be elimination of etiological factors in the root canal system rather than their product, apical true cyst. A 10 year old female patient reported to the Department of Pedodontics and Preventive Dentistry, Dr R Ahmed Dental Coll...

OBJECTIVE The purpose of this study was to evaluate the efficacy of auxiliary chemical substances and intracanal medications on Escherichia coli and its endotoxin in root canals. MATERIAL AND METHODS Teeth were contaminated with a suspension of E. coli for 14 days and divided into 3 groups according to the auxiliary chemical substance used: G1) 2.5% sodium hypochlorite (NaOCl); G2) 2% chlorhe...

BACKGROUND AND AIM: The aim of the present study was to evaluate the effect of different needle-insertion depths on the accuracy of the Root ZX II and Root ZX mini apex locators in the presence of various irrigants. METHODS: Ninety extracted single-canal human teeth were used in nine experimental groups. The coronal one-third of the canals was preflared, and the length to the major foramen was ...

Mineral trioxide aggregate (MTA) is a material that has been used worldwide in several clinical applications, such as apical barriers in teeth with immature apices, repair of root perforations, root-end filling, pulp capping, and pulpotomy. The purpose of this case report was to describe successful revascularization treatment of an immature mandibular right second premolar with apical periodont...