Introduction: Lignocaine with adrenaline is used with local anaesthetics to improve the onset and increase the duration of nerve block. The present study aimed to evaluate it's effect when used together with ropivacaine. Objective: To evaluate the effect of adding 2% lignocaine with adrenaline to 0.5% ropivacaine, for supraclavicular brachial plexus blockade on the onset and duration of sensory...

BACKGROUND AND OBJECTIVES This study evaluated the effects of clonidine on anesthesia onset, quality and duration of analgesia of sciatic nerve block using 0.5% ropivacaine. METHODS Forty adult patients scheduled for foot or lateral aspect of the ankle procedures under combined anterior femoral/sciatic nerves block were randomly assigned to group 1, receiving 25 mL of 0.5% ropivacaine plus pl...

BACKGROUND Sex differences, which may be an important variable for determining anesthetic requirements, have not been well investigated in the aspect of local anesthetic. This investigation aimed to compare the minimum local analgesic concentration (MLAC) of ropivacaine for ultrasound-guided supraclavicular brachial plexus block (US-SCB) between men and women. MATERIAL AND METHODS Patients ag...

BACKGROUND Blockade of the ilioinguinal and iliohypogastric nerves is a useful procedure in paediatric patients undergoing inguinal surgery. Bupivacaine 2 mg kg-1 has been recommended for this block. We compared the plasma concentrations of ropivacaine and bupivacaine following an ilioinguinal-iliohypogastric block. METHODS Forty children scheduled for elective inguinal surgery were randomize...

OBJECTIVE Although intrathecal drug infusion has been commonly adopted for terminal cancer pain relief, its adverse effects have made many clinicians reluctant to employ it for intractable cancer pain. The objective of this study is to compare the efficacy and security of an intrathecal continuous infusion of morphine and ropivacaine versus intrathecal morphine alone for cancer pain. METHODS ...

Background: Several clinical studies have shown that clonidine prolongs sensory motor blockade when used with bupivacaine but ideal doses of clonidine on ropivacaine is not well defined and to evaluate the effect of two doses of clonidine on ropivacaine, for supraclavicular brachial plexus blockade. Methods: In a prospective randomized double blind study supraclavicular brachial plexus blockade...

Ropivacaine, introduced in 1995, is an amide-type local anaesthetic. It consists of pure optical S-(-)-isomers and has a low cardiotoxicity. We report delayed hypersensitivity reactions to ropivacaine. A 74 year old man with postherpetic neuralgia started taking amitriptyline, alprazolam, and loxoprofen and underwent an epidural block with 0.2% ropivacaine hydrochloride without preservatives (4...

BACKGROUND It remains unknown whether local anesthetic concentration, or simply total drug dose, is the primary determinant of continuous peripheral nerve block effects. We therefore tested the null hypothesis that providing different concentrations and rates of ropivacaine, but at equal total doses, produces comparable effects when used in a continuous sciatic nerve block in the popliteal foss...

BACKGROUND The study was designed to determine and compare the median effective doses (MEDs) of intrathecal ropivacaine with levobupivacaine for labor analgesia. METHODS In this double-blind study, 100 parturients in early labor were randomized to receive either intrathecal ropivacaine or levobupivacaine. For each drug, the patients were assigned to receive one of the five doses studied, name...

BACKGROUND This study aims to investigate differences between continuous epidural infusion (CEI) and programmed intermittent epidural bolus (IEB) analgesia for the Chinese parturients undergoing spontaneous delivery and to approach their safety to parturients and neonates. METHODS Two hundred healthy American Society of Anesthesiologists class I or II, term (≥37 weeks' gestation), nulliparous...