نتایج جستجو برای: s aureus

تعداد نتایج: 752096  

Journal: :iranian journal of basic medical sciences 0
mohammad f haroun faculty of pharmacy, al andalus university for medical sciences, syria rawaa s al-kayali faculty of pharmacy, aleppo university, syria public health department, center for strategic studies and research, aleppo university, syria

objective(s): to evaluate the in vitro interaction between different extracts of thymbra spicata l. and certain antimicrobial drugs of different mechanisms, including ampicillin, cefotaxime, amikacin and ciprofloxacin. this study was performed against multidrug-resistant strains of staphylococcus aureus and klebsiella pneumoniae. materials and methods: evaluation of antibacterial activity and s...

Journal: :Journal of immunology 2013
Keven M Robinson Sun Mi Choi Kevin J McHugh Sivanarayana Mandalapu Richard I Enelow Jay K Kolls John F Alcorn

Pneumonia is a leading cause of death worldwide. Staphylococcal aureus can be a cause of severe pneumonia alone or a common pathogen in secondary pneumonia following influenza. Recently, we reported that preceding influenza attenuated the Type 17 pathway, increasing the lung's susceptibility to secondary infection. IL-1β is known to regulate host defense, including playing a role in Th17 polari...

Journal: :Archives of pediatrics & adolescent medicine 2012
Stephanie A Fritz Patrick G Hogan Genevieve Hayek Kimberly A Eisenstein Marcela Rodriguez Melissa Krauss Jane Garbutt Victoria J Fraser

OBJECTIVES To measure prevalence of Staphylococcus aureus colonization in household contacts of children with acute S aureus skin and soft tissue infections (SSTI), determine risk factors for S aureus colonization in household contacts, and assess anatomic sites of S aureus colonization in patients and household contacts. DESIGN Cross-sectional study. SETTING St Louis Children's Hospital Em...

Journal: :Molecules 2011
Bing-Feng Leng Jia-Zhang Qiu Xiao-Han Dai Jing Dong Jian-Feng Wang Ming-Jing Luo Hong-En Li Xiao-Di Niu Yu Zhang Yong-Xing Ai Xu-Ming Deng

Staphylococcus aureus causes a broad range of life-threatening diseases in humans. The pathogenicity of this micro-organism is largely dependent upon its virulence factors. One of the most extensively studied virulence factors is the extracellular protein α-toxin. In this study, we show that allicin, an organosulfur compound, was active against S. aureus with MICs ranged from 32 to 64 μg/mL. Ha...

Journal: :The Journal of infectious diseases 2012
Chahnaz Kebaier Robin R Chamberland Irving C Allen Xi Gao Peter M Broglie Joshua D Hall Corey Jania Claire M Doerschuk Stephen L Tilley Joseph A Duncan

Staphylococcus aureus is a dangerous pathogen that can cause necrotizing infections characterized by massive inflammatory responses and tissue destruction. Staphylococcal α-hemolysin is an essential virulence factor in severe S. aureus pneumonia. It activates the nucleotide-binding domain and leucine-rich repeat containing gene family, pyrin domain containing 3 (NLRP3) inflammasome to induce pr...

2015
Per Skallerup Carmen Espinosa-Gongora Claus B. Jørgensen Luca Guardabassi Merete Fredholm

BACKGROUND Staphylococcus aureus is an important human opportunistic pathogen residing on skin and mucosae of healthy people. Pigs have been identified as a source of human colonization and infection with methicillin-resistant Staphylococcus aureus (MRSA) and novel measures are needed to control zoonotic transmission. A recent longitudinal study indicated that a minority of pigs characterized b...

2017
Nana Ama Amissah Andrew H. Buultjens Anthony Ablordey Lieke van Dam Ampomah Opoku-Ware Sarah L. Baines Dieter Bulach Caitlin S. Tetteh Isaac Prah Tjip S. van der Werf Alexander W. Friedrich Torsten Seemann Jan Maarten van Dijl Ymkje Stienstra Timothy P. Stinear John W. Rossen

Objectives:Staphylococcus aureus infections in burn patients can lead to serious complications and death. The frequency of S. aureus infection is high in low- and middle-income countries presumably due to limited resources, misuse of antibiotics and poor infection control. The objective of the present study was to apply population genomics to precisely define, for the first time, the transmissi...

Objective(s): In the current research, the prevalence of Staphylococcus aureus clones and genes encoding antimicrobial resistance and toxins were examined among 120 S. aureus strains from nosocomial infections in tehran, Iran.Materials and Methods: Antimicrobial susceptibility was examined, based on disk diffusion and PCR method to identify resistance and toxin-encoding genes. Based on the poly...

2017
Ilse Vandecandelaere Filip Van Nieuwerburgh Dieter Deforce Tom Coenye

In this paper, the metabolic activity in single and dual species biofilms of Staphylococcus epidermidis and Staphylococcus aureus isolates was investigated. Our results demonstrated that there was less metabolic activity in dual species biofilms compared to S. aureus biofilms. However, this was not observed if S. aureus and S. epidermidis were obtained from the same sample. The largest effect o...

2015
Yu Liu Jiannan Feng Qiang Lu Xin Zhang Yaping Gao Jun Yan Chunhua Mu Yan Hei Ming Lv Gencheng Han Guojiang Chen Peng Jin Weiguo Hu Beifen Shen Guang Yang

Staphylococcus aureus causes a wide range of infectious diseases. Treatment of these infections has become increasingly difficult due to the widespread emergence of antibiotic-resistant strains; therefore, it is essential to explore effective alternatives to antibiotics. A secreted protein of S. aureus, known as eLtaS, is an extracellular protein released from the bacterial membrane protein, Lt...

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